IMMUNOMODULATION USING SPORES AND POLLEN GRAINS
    8.
    发明公开
    IMMUNOMODULATION USING SPORES AND POLLEN GRAINS 审中-公开
    莫桑比克麻省理工学院

    公开(公告)号:EP2906257A1

    公开(公告)日:2015-08-19

    申请号:EP13846840.0

    申请日:2013-10-14

    摘要: The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen/spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen/spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner cavity and one or more antigens disposed on the outer surface, in the inner cavity, in the multiple pores, or a combination thereof, wherein the one or more antigens modulate an immune responses in the subject.

    摘要翻译: 本发明包括通过提供一种疫苗组合物制备和使用该组合物来调节受试者的免疫应答的组合物,方法,所述疫苗组合物具有放置在药物载体中的用于递送至受试者的花粉/孢子,其中所述花粉/孢子包含多个孔 其将花粉/孢子的外表面连接到内腔和设置在外表面,内腔中,多孔中或其组合中的一种或多种抗原,其中所述一种或多种抗原调节免疫应答 在主题。

    METHOD AND APPARATUS FOR GENDER SELECTION BASED ON PH
    10.
    发明公开
    METHOD AND APPARATUS FOR GENDER SELECTION BASED ON PH 审中-公开
    方法和装置性别选择pH值BASE

    公开(公告)号:EP2121901A2

    公开(公告)日:2009-11-25

    申请号:EP07871320.3

    申请日:2007-10-31

    IPC分类号: C12N5/00 C12N5/02

    CPC分类号: C12M47/04 C12N5/0612

    摘要: The present invention includes methods and apparatus to separate X or Y-chromosome bearing sperm cells in a population by first placing the population of sperm cells at physiological pH environment, and simultaneously contacting the population of sperm cells with one or more additional sub-environments with different pH values. The exposure allows mobile sperm cells bearing X or Y-chromosome to migrate to the different pH sub-environments, wherein each cell only exposed or come in contact with one pH sub-environment. Finally, the collecting X or Y- chromosome enriched population of sperm cells is performed.