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1.发明公开PARTICLE SIZE REDUCTION OF AN ANTIMUSCARINIC COMPOUND 有权VERRINGERUNG DERTEILCHENGRÖSSEEINER抗生素VERBINDUNG公开(公告)号：EP2988728A1
公开(公告)日：2016-03-02
申请号：EP14724332.3
申请日：2014-04-24
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： PASQUALI, Irene , CASAZZA, Andrea , SAUNDERS, Mark , LOSI, Elena
CPC classification number: A61K9/1688 , A61K9/0075 , A61K9/008 , A61K9/14 , A61K31/40
Abstract: A stable crystalline micronized particulate of a glycopyrronium salt may be prepared by suspending the drug in a water-immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.
Abstract translation: 糖基铵盐的稳定的结晶微粉化颗粒可以通过将药物悬浮在水不混溶的抗溶剂中来制备，其中药物几乎不溶解或不溶解并使悬浮液微粉化。 所得到的药物颗粒在储存时的结块和/或聚集方面物理上是稳定的。
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2.发明公开
公开(公告)号：EP3409270A1
公开(公告)日：2018-12-05
申请号：EP18178893.6
申请日：2014-07-10
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MUSA, Rossella , PASQUALI, Irene , ASKEY-SARVAR, Azita , SCHIARETTI, Francesca
IPC: A61K9/00 , A61K47/12 , A61K47/26 , A61K31/167 , A61K31/40 , A61K31/573
CPC classification number: A61K9/0075 , A61J3/02 , A61K9/145 , A61K31/167 , A61K31/40 , A61K31/573 , A61K45/06 , A61M15/00 , Y10S514/958 , A61K2300/00
Abstract: The invention relates to dry powder formulations for inhalation comprising a combination of an anti-cholinergic, a long-acting beta 2 -adrenoceptor agonist, and a corticosteroid, their process of preparation and therapeutic uses thereof.
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3.发明公开DRY POWDER FORMULATION COMPRISING A CORTICOSTEROID AND A BETA-ADRENERGIC FOR ADMINISTRATION BY INHALATION 审中-公开干粉制剂与皮质类固醇和β肾上腺素通过吸入给药
公开(公告)号：EP3020394A1
公开(公告)日：2016-05-18
申请号：EP15202117.6
申请日：2013-01-23
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/573 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
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4.发明公开DRY POWDER FORMULATION COMPRISING A CORTICOSTEROID AND A BETA-ADRENERGIC FOR ADMINISTRATION BY INHALATION 有权EINEM BETA-ADRENERGIKUM ZUR VERABREICHUNG MITTELS INHALATION的TROCKENPULVERFORMULIERUNG MIT EINEM CORTICOSTEROID
公开(公告)号：EP2806855A1
公开(公告)日：2014-12-03
申请号：EP13704372.5
申请日：2013-01-23
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/57 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
Abstract translation: 本发明涉及一种组合包含皮质类固醇和β2-肾上腺素能药物的干粉制剂，其制备方法及其治疗用途。
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公开(公告)号：EP3505209B1
公开(公告)日：2020-11-18
申请号：EP19154989.8
申请日：2015-06-19
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： TAMPIERI, Valerio , ZUCCHERI, Lorenzo , ILANDI, Emiliano , CAMPANINI, Alice , PASQUALI, Irene , LINNANE, Patrick Gerard , HAWSON, Nicholas Lee , GALE, David , GARRAD, Joanne
IPC: A61M15/00
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公开(公告)号：EP3019153B1
公开(公告)日：2018-09-05
申请号：EP14747855.6
申请日：2014-07-10
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MUSA, Rossella , PASQUALI, Irene , ASKEY-SARVAR, Azita , SCHIARETTI, Francesca
IPC: A61K9/00 , A61K47/12 , A61K47/26 , A61K31/167 , A61K31/40 , A61K31/573
CPC classification number: A61K9/0075 , A61J3/02 , A61K9/145 , A61K31/167 , A61K31/40 , A61K31/573 , A61K45/06 , A61M15/00 , Y10S514/958 , A61K2300/00
Abstract: Dry powder formulations for inhalation comprising a combination of an anticholinergic, a long-acting beta2-adrenoceptor agonist, and a corticosteroid are useful for the prevention and/or treatment of inflammatory and/or obstructive airways diseases.
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公开(公告)号：EP2806855B1
公开(公告)日：2018-07-11
申请号：EP13704372.5
申请日：2013-01-23
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/57 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
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8.发明公开
公开(公告)号：EP3412277A1
公开(公告)日：2018-12-12
申请号：EP18181331.2
申请日：2013-01-23
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/57 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
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9.发明公开DRY POWDER FORMULATION COMPRISING AN ANTICHOLINERGIC, A CORTICOSTEROID AND A BETA-ADRENERGIC FOR ADMINISTRATION BY INHALATION 有权干粉制剂抗胆碱能药物，皮质类固醇和β-肾上腺素通过吸入给药
公开(公告)号：EP3019153A1
公开(公告)日：2016-05-18
申请号：EP14747855.6
申请日：2014-07-10
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MUSA, Rossella , PASQUALI, Irene , ASKEY-SARVAR, Azita , SCHIARETTI, Francesca
IPC: A61K9/00 , A61K47/12 , A61K47/26 , A61K31/167 , A61K31/40 , A61K31/573
CPC classification number: A61K9/0075 , A61J3/02 , A61K9/145 , A61K31/167 , A61K31/40 , A61K31/573 , A61K45/06 , A61M15/00 , Y10S514/958 , A61K2300/00
Abstract: Dry powder formulations for inhalation comprising a combination of an anticholinergic, a long-acting beta2-adrenoceptor agonist, and a corticosteroid are useful for the prevention and/or treatment of inflammatory and/or obstructive airways diseases.
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公开(公告)号：EP2988728B1
公开(公告)日：2019-08-21
申请号：EP14724332.3
申请日：2014-04-24
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： PASQUALI, Irene , CASAZZA, Andrea , SAUNDERS, Mark , LOSI, Elena
