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公开(公告)号：EP0594696B1
公开(公告)日：1997-04-16
申请号：EP92914963.1
申请日：1992-07-15
申请人： SINVENT A/S
IPC分类号： C08F8/00 , C08F291/00 , C08J3/03
摘要： Process for producing a dispersion, wherein dispersed slightly crosslinked polyvinyl seed particles are swollen with an ionizing liquid, said seed particles containing covalently linked ionizable groups causing a swelling of the seed particles by the ionizing liquid to form a dispersion of droplets, wherein the resulting droplets after the swelling have a volume which is at least 5 times that of the seed particles. Said ionizing liquid may be or contain a polymerizable monomer or be charged with such a monomer. Polymerization of the monomers is effected in the droplets during or after the swelling, to form polymer particles.
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公开(公告)号：EP0688430A1
公开(公告)日：1995-12-27
申请号：EP94909179.0
申请日：1994-03-10
申请人： SINVENT A/S
发明人： UGELSTAD, John , STENSTAD, Per , KILAAS, Lars , BERGE, Arvid
CPC分类号： G01N33/54353 , C12N11/06 , G01N33/5434 , G01N2446/90
摘要： The present invention provides a method of linking a target particle to an insoluble support, wherein said particle is bound to said support by means of a specific binding partner, characterised in that the linkage between said binding partner and said support comprises a hydroxyboryl/cis-diol bond. The invention has particular utility in the immobilisation and isolation of cells.
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公开(公告)号：EP0782704A1
公开(公告)日：1997-07-09
申请号：EP95930638.0
申请日：1995-09-05
申请人： SINVENT A/S
IPC分类号： G01N33
CPC分类号： G01N33/5306 , G01N33/50 , G01N33/54353
摘要： The present invention provides the use of a milk protein to block the non-specific binding of cells to a solid phase selective cell-capture matrix. Generally speaking, the solid phase selective capture matrix will be a solid support adapted for the selective separation of target cells by means of a target-specific binding partner such as an antibody.
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公开(公告)号：EP0688430B1
公开(公告)日：1997-05-28
申请号：EP94909179.7
申请日：1994-03-10
申请人： SINVENT A/S
发明人： UGELSTAD, John , STENSTAD, Per , KILAAS, Lars , BERGE, Arvid
IPC分类号： G01N33/547 , G01N33/563 , C12Q1/34 , C12N11/06
CPC分类号： G01N33/54353 , C12N11/06 , G01N33/5434 , G01N2446/90
摘要： The present invention provides a method of linking a target particle to an insoluble support, wherein said particle is bound to said support by means of a specific binding partner, characterised in that the linkage between said binding partner and said support comprises a hydroxyboryl/cis-diol bond. The invention has particular utility in the immobilisation and isolation of cells.
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公开(公告)号：EP0594696A1
公开(公告)日：1994-05-04
申请号：EP92914963.0
申请日：1992-07-15
申请人： SINVENT A/S
IPC分类号： C08L25 , C01B31 , C08F8 , C08F12 , C08F20 , C08F22 , C08F291 , C08G8 , C08G12 , C08G18 , C08G59 , C08G65 , C08G85 , C09C1
摘要： L'invention se rapporte à un procédé pour la production d'une dispersion, dans lequel des particules d'ensemencement polyvinyliques légèrement réticulées et dispersées sont amenées à gonfler au moyen d'un liquide ionisant. Ces particules d'ensemencement contiennent des groupes ionisables liés par covalence, qui provoquent le gonflement des particules d'ensemencement par le liquide ionisant, afin de former une dispersion de goutellettes, les goutellettes ainsi produites présentant après gonflement un volume égal au moins à cing fois celui des particules d'ensemencement. Le liquide ionisant peut être constitué par un monomère polymérisable ou contenir un tel monomère ou être chargé d'un tel monomère. La polymérisation des monomères est effectuée dans les goutellettes pendant ou après le gonflement, pour former des particules polymères.
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