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公开(公告)号：EP3347451A1
公开(公告)日：2018-07-18
申请号：EP16778499.0
申请日：2016-09-09
Applicant: The General Hospital Corporation
Inventor： REN, Xi , OTT, Harald C.
CPC classification number: C12N5/0697 , C12M21/08 , C12M25/14 , C12M41/48 , C12N5/0688 , C12N2500/02 , C12N2500/25 , C12N2501/01 , C12N2501/11 , C12N2501/115 , C12N2501/135 , C12N2501/15 , C12N2501/155 , C12N2501/165 , C12N2501/17 , C12N2501/39 , C12N2501/415 , C12N2502/1388 , C12N2502/27 , C12N2502/28 , C12N2506/45 , C12N2533/92
Abstract: A method for vascular regeneration comprises delivering endothelial cells to a lung scaffold, delivering perivascular cells to the lung scaffold, and providing a multiphase culture program to the scaffold. The multiphase culture program comprises a first phase including delivering an angiogenic medium, e.g., having 40-100 ng/ml of pro-angiogenic factors, and a second phase including delivering a stabilization medium, e.g., having 0.5-2% of serum and 1-20 ng/ml of angiogenic factors.
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2.发明公开
公开(公告)号：EP3471703A1
公开(公告)日：2019-04-24
申请号：EP17814104.0
申请日：2017-06-15
Applicant: The General Hospital Corporation
Inventor： OTT, Harald C. , REN, Xi , BLOOM, Jordan P. , RAJAB, Taufiek Konrad
IPC: A61K9/14 , A61K31/715 , C12N5/07 , C12N5/02 , C12N5/00 , A61N1/30 , C07D233/88
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公开(公告)号：EP3347451B1
公开(公告)日：2019-08-28
申请号：EP16778499.0
申请日：2016-09-09
Applicant: The General Hospital Corporation
Inventor： REN, Xi , OTT, Harald C.
