摘要:
The invention relates to a device for locating one or more mobile elements in a predetermined zone, this device comprising: - at least one module on board the mobile element, this onboard module comprising an electronic circuit and at least one coil on board for emitting a locating signal, - a power supply for this onboard module, - a matrix of receiving coils distributed in rows and columns on a support in proximity to the predetermined zone. According to the invention the rows and columns of the matrix of receiving coils are independent and each row and each column consists of several receiving coils connected in series; each coil having the function of picking up said locating signal when the mobile element is in proximity; this device furthermore comprising: - a processing unit connected to the matrix of receiving coils for determining in real time the placement of the mobile element in the predetermined zone by detecting a signal level on each row and each column.
摘要:
The invention relates to a method for measuring one or more diaphragmatic functional parameters, said method comprising the steps consisting of: - a) a stimulation step by which a stimulation of the diaphragm is provided to generate a movement of one or more parts of the diaphragm, - b) during the movement of said one or more parts of the diaphragm, imaging one or more parts of the diaphragm over time through an imaging step comprising the steps of emitting unfocused ultrasound waves, detecting ultrasound waves reflected and/or scattered by organic tissues, processing the reflected and/or scattered ultrasound waves over time to generate images by technical means, - c) processing, by technical means, images previously acquired during the imaging step to measure one or more movements of the diaphragm over time, and/or a propagation of a movement through the diaphragm over time, and/or a propagation speed of a movement through the diaphragm over time, and/or one or more movements of different parts of the diaphragm over time, and/or an amplitude of a movement of the diaphragm over time, and/or a time separating the stimulation of the diaphragm from the occurrence of a movement of the diaphragm associated to said stimulation, - d) based on one or more measurements of the processing step, determining one or more functional parameters of the diaphragm by technical means.
摘要:
The present invention relates to a gene therapy vector which is useful in the treatment or prevention of hypertrophic cardiomyopathy in a subject in need thereof. The gene therapy vector of the invention comprises a nucleic acid sequence encoding a cardiac sarcomeric protein and a cardiomyocyte-specific promoter which is operably linked to said nucleic acid sequence. The invention furthermore relates to a cell which comprises the gene therapy vector. Pharmaceutical compositions which comprise the gene therapy vector and/or a cell comprising said vector are also provided. In another aspect, the invention relates to a method for treating or preventing hypertrophic cardiomyopathy in a subject by introducing the gene therapy vector of the invention into a subject in need of treatment.
摘要:
The invention relates to a system for measuring a palmar gripping force, comprising a device (1) for measuring said palmar gripping force, which device comprises: a handle configured to receive a palmar gripping force; a force sensor (3); and an electronic module (6) integrated into the device and comprising at least one microcontroller (61) connected to the sensor (3) and able to process data originating from said sensor (3), characterised in that the force sensor comprises a stress gauge with a minimum precision of 50 g; a controlling system is also provided and comprises means able to do the following: calibrate the sensor using a linear calibration curve; and transmit the sensor measurements to a display unit (8) and/or a storage unit and/or a processing unit, preferably via wired or wireless means.