公开(公告)号：EP3115374B1

公开(公告)日：2022-01-19

申请号：EP16182666.4

申请日：2004-12-06

发明人： Stauss, Hans Josef ,  Gao, Liquan ,  Xue, Shao-An

IPC分类号： A61P35/00 ,  C07K14/725 ,  A61P35/02

公开(公告)号：EP3743955A1

公开(公告)日：2020-12-02

申请号：EP19702696.6

申请日：2019-01-25

申请人： UCL BUSINESS LTD ,  Imperial Innovations Limited

发明人： BRETT, Daniel ,  BROWN, Leon ,  MASON, Thomas ,  DEDIGAMA, Ishanka ,  KUCERNAK, Anthony

IPC分类号： H01M8/18 ,  H01M2/16 ,  H01M4/96 ,  H01M8/0228

公开(公告)号：EP2622231B1

公开(公告)日：2020-01-15

申请号：EP11764603.4

申请日：2011-09-22

申请人： Imperial Innovations Limited

发明人： VASSILICOS, John Christos

IPC分类号： F15D1/10

公开(公告)号：EP3525689A1

公开(公告)日：2019-08-21

申请号：EP17787541.6

申请日：2017-10-10

申请人： Imperial Innovations Limited

发明人： SODERGREN, Mikael ,  PAYNE, Christopher

IPC分类号： A61B17/122 ,  A61B17/128 ,  A61F5/00

公开(公告)号：EP3515366A1

公开(公告)日：2019-07-31

申请号：EP17777640.8

申请日：2017-09-20

申请人： Imperial Innovations Limited

发明人： JEFFERS, Jonathan ,  VAN ARKEL, Richard ,  GHOUSE, Shaaz ,  RAY, Sebastian

IPC分类号： A61F2/30

公开(公告)号：EP2828753B1

公开(公告)日：2019-05-08

申请号：EP13800730.7

申请日：2013-03-14

申请人： Triad National Security, LLC ,  Imperial Innovations Limited

发明人： NEIL, Joshua, Charles ,  TURCOTTE, Melissa ,  HEARD, Nicholas, Andrew

IPC分类号： H04L29/06 ,  H04L1/00 ,  G06N5/02 ,  G06N7/00 ,  G06F21/57

公开(公告)号：EP3453099A1

公开(公告)日：2019-03-13

申请号：EP17723744.3

申请日：2017-05-04

申请人： Imperial Innovations Limited

发明人： MITCHESON, Paul ,  YATES, David ,  ALDHAHER, Samer

IPC分类号： H02J50/12 ,  H02M7/537

摘要： A load-independent Class EF inverter may maintain ZVS operation, and produce a constant output current, rather than a constant output voltage, regardless of the load resistance. A constant output current allows the inverter to operate efficiently for a load range from zero resistance (short circuit) to a certain maximum load resistance, making the inverter more suitable as a coil driver for an IPT system. The resonant frequency of the resonant circuit may be tuned to a non-integer multiple of a switching frequency.

公开(公告)号：EP3452474A1

公开(公告)日：2019-03-13

申请号：EP17723482.0

申请日：2017-05-05

申请人： Imperial Innovations Limited

发明人： WADSWORTH, Andrew ,  NIELSEN, Christian ,  HOLLIDAY, Sarah ,  MCCULLOCH, Iain ,  KIRKUS, Mindaugas ,  BARAN, Derya ,  ASHRAF, Shahid

IPC分类号： C07D417/14 ,  C07D495/04 ,  C07F7/30 ,  H01L51/00

公开(公告)号：EP3043737B1

公开(公告)日：2019-01-16

申请号：EP14766782.8

申请日：2014-09-10

申请人： Imperial Innovations Limited

发明人： MYLONAS, George ,  YANG, Guang-Zhong ,  DARZI, Ara ,  CUNDY, Thomas

IPC分类号： A61B34/00 ,  A61B18/14 ,  A61B18/00

公开(公告)号：EP3411501A1

公开(公告)日：2018-12-12

申请号：EP17708567.7

申请日：2017-02-03

申请人： Imperial Innovations Limited

发明人： LALVANI, Ajit ,  HOANG, Long ,  NIAZI, Umar

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/158 ,  C12Q2600/16

摘要： A method for diagnosing active tuberculosis (ATB) in an individual comprising of the steps of; providing a sample to be tested from the individual; measuring the expression in the test sample of GBP6 (guanylate binding protein 6) and/or BATF2 (basic leucine zipper ATF-like transcription factor 2), wherein the expression in the test sample of GBP6 and/or BATF2 is indicative of the presence of active tuberculosis in the individual. In some embodiments, the levels of expression in the test sample are compared to the expression in a control sample from a healthy individual and/or an individual afflicted with active tuberculosis (ATB). Also claimed is a binding agent specific for GBP6 or BATF2, for determining the presence of ATB in an individual. Additionally, a nucleic acid molecule encoding GBP6 or BATF2, or a binding moiety specific therefor, for determining the presence of ATB in an individual. A kit for determining the presence of an ATB infection in an individual is also disclosed, comprising one or more binding agents against GBP6 or BATF2 or other additional biomarkers and instructions for performing the claimed method.