MASSIVELY PARALLEL DNA SEQUENCING APPARATUS
    5.
    发明公开

    公开(公告)号:EP3408219A1

    公开(公告)日:2018-12-05

    申请号:EP17745013.7

    申请日:2017-01-27

    IPC分类号: B82Y15/00 C12Q1/68

    CPC分类号: G01N33/48721

    摘要: A DNA or genome sequencing structure is disclosed. The structure includes an electrode pair, each electrode having a tip-shaped end, the electrodes separated by a nanogap defined by facing tip-shaped ends; at least one conductive island deposited at or near each tip-shaped end; and a biomolecule having two ends, each end attached to the conductive islands in the electrode pair such that one biomolecule bridges over the nanogap in the electrode pair, wherein nucleotide interactions with the biomolecule provides electronic monitoring of DNA or genome sequencing without the use of a fluorescing element.