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公开(公告)号:EP3676389A1
公开(公告)日:2020-07-08
申请号:EP18849718.4
申请日:2018-08-30
发明人: MERRIMAN, Barry , GEISER, Tim , MOLA, Paul , COSTA, Gina
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公开(公告)号:EP3545076A1
公开(公告)日:2019-10-02
申请号:EP17874229.2
申请日:2017-11-22
发明人: CHOI, Chulmin , JIN, Sungho , MERRIMAN, Barry, L. , MOLA, Paul , GEISER, Tim
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公开(公告)号:EP3314245A1
公开(公告)日:2018-05-02
申请号:EP16815467.2
申请日:2016-06-24
IPC分类号: G01N27/26 , G01N27/327
CPC分类号: C12Q1/6869 , B82Y15/00 , B82Y40/00 , G01N27/26 , G01N27/327 , G01N27/3272 , G01N27/3276 , G01N27/3278 , G01N27/4145
摘要: Electronic sensors configured to detect single molecule targets and methods of using and manufacturing such electronic sensors are disclosed. A sensor may include a first electrode and a second electrode separated by a sensor gap. The first and second electrodes can be coupled by a sensor complex that can include a biopolymer bridge molecule and a probe. The probe can interact with a target molecule, and interaction of the probe and target molecule can produce a signal suitable to provide detection of the target molecule.
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公开(公告)号:EP3568407A1
公开(公告)日:2019-11-20
申请号:EP18739158.6
申请日:2018-01-10
发明人: MERRIMAN, Barry, L. , GEISER, Tim , MOLA, Paul
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公开(公告)号:EP3408219A1
公开(公告)日:2018-12-05
申请号:EP17745013.7
申请日:2017-01-27
CPC分类号: G01N33/48721
摘要: A DNA or genome sequencing structure is disclosed. The structure includes an electrode pair, each electrode having a tip-shaped end, the electrodes separated by a nanogap defined by facing tip-shaped ends; at least one conductive island deposited at or near each tip-shaped end; and a biomolecule having two ends, each end attached to the conductive islands in the electrode pair such that one biomolecule bridges over the nanogap in the electrode pair, wherein nucleotide interactions with the biomolecule provides electronic monitoring of DNA or genome sequencing without the use of a fluorescing element.
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公开(公告)号:EP3615685A1
公开(公告)日:2020-03-04
申请号:EP18790713.4
申请日:2018-04-25
IPC分类号: C12Q1/68 , G01N27/327 , G01N27/414 , G01N33/487
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公开(公告)号:EP3571286A1
公开(公告)日:2019-11-27
申请号:EP17893481.6
申请日:2017-11-22
发明人: CHOI, Chulmin , JIN, Sungho , MERRIMAN, Barry, L. , MOLA, Paul , GEISER, Tim
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公开(公告)号:EP3953491B1
公开(公告)日:2023-12-06
申请号:EP20787061.9
申请日:2020-04-13
发明人: MERRIMAN, Barry , GEISER, Tim , MOLA, Paul , RIDEOUT, Darryl
IPC分类号: C12Q1/6825 , G01N27/327 , G01N33/543 , H01G4/14 , H01G4/18 , H01B1/04
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公开(公告)号:EP3414784B1
公开(公告)日:2021-04-14
申请号:EP17750776.1
申请日:2017-02-09
发明人: CHOI, Chulmin , JIN, Sungho , MOLA, Paul, W. , MERRIMAN, Barry L.
IPC分类号: G01N27/327
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