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公开(公告)号：EP3613765B1
公开(公告)日：2024-10-02
申请号：EP19187268.8
申请日：2013-08-02
CPC classification number: A61K2039/50520130101 , C07K2317/56520130101 , C07K2317/7620130101 , C07K16/2827 , C07K16/28 , A61P11/00 , A61P37/00
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公开(公告)号：EP4431110A2
公开(公告)日：2024-09-18
申请号：EP24187471.8
申请日：2020-01-19
Applicant: Chineo Medical Technology Co., Ltd.
Inventor： GU, Weiyue
IPC: A61K39/00
CPC classification number: A61P35/00 , C07K2319/0320130101 , C12N2510/0020130101 , C12N5/0636 , C07K16/32 , C07K16/2803 , C12N2740/1504120130101 , C07K2317/9220130101 , C07K16/2827 , C07K14/70521 , C07K14/70578 , C07K14/70532 , C07K14/70503 , C07K14/70596 , C07K2319/0020130101 , A61K39/4631 , A61K39/464401 , A61K39/4632 , A61K39/4611 , A61K39/464412 , A61K2239/3820230501 , A61K39/4636 , A61K2239/3120230501 , A61K39/464488
Abstract: The present invention provides an enhanced receptor for improving the function of an immune cell, and a composition and a cell related thereto. The enhanced receptor is a transmembrane protein, which is a fusion protein consisting of an extracellular domain and an intracellular domain, wherein the extracellular domain is capable of binding to a target cell and activating the signaling function of the intracellular domain, thereby increasing the activation level of the immune cell, and overcoming the inhibition of the target cell microenvironment on the immune cell, thus enhancing the effect of immunotherapy.
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公开(公告)号：EP4429769A1
公开(公告)日：2024-09-18
申请号：EP22823261.7
申请日：2022-11-09
Applicant: Sensei Biotherapeutics, Inc.
Inventor： PIERCE, Robert , VAN DER HORST, Edward H. , THISTED, Thomas , BOLAND, Nadthakarn , NIELSON, Nels
CPC classification number: C07K16/2827 , C07K2317/2120130101 , C07K2317/7620130101 , A61K2039/50520130101 , C07K2317/9420130101 , A61K2039/57220130101 , A61K2039/50720130101 , C07K16/2818 , C07K2317/3420130101 , C07K2317/9220130101 , A61P35/00
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公开(公告)号：EP4413046A2
公开(公告)日：2024-08-14
申请号：EP22879457.4
申请日：2022-10-05
Applicant: Board of Regents, The University of Texas System , Eberhard Karls Universität Tübingen, Medizinische Fakultät
Inventor： BATTULA, Venkata Lokesh , BUHRING, Hans-Jorg
IPC: C07K16/28 , A61K39/395 , A61P35/00 , C07K14/705 , G01N33/574
CPC classification number: C07K2317/7620130101 , C07K16/2827 , C07K2317/7320130101 , A61P35/00 , C07K2317/2420130101 , A61K2039/50520130101 , C07K2317/3420130101
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公开(公告)号：EP4412635A1
公开(公告)日：2024-08-14
申请号：EP22809608.7
申请日：2022-10-06
Applicant: CytomX Therapeutics, Inc.
Inventor： BEREZHNOY, Alexey Yevgenyevich , PUYADE, Nicole G. , CAI, Na , WINTER, Michael B. , WONG, Kenneth , PAIDHUNGAT, Madan M. , DANIEL, Dylan L. , LE SCOLAN, Erwan
CPC classification number: C07K19/00 , A61P35/00 , C07K16/2827 , A61K39/39558 , C07K14/52 , C07K2319/0020130101 , A61K39/39 , A61K45/06 , A61K38/21
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公开(公告)号：EP4408397A1
公开(公告)日：2024-08-07
申请号：EP22875346.3
申请日：2022-09-30
Applicant: National Centre For Cell Science
Inventor： LAL, Girdhari , KARMAKAR, Surojit
CPC classification number: A61P35/00 , A61K45/06 , A61K31/495 , A61K31/505 , A61K31/4439 , A61K31/519 , A61K31/337 , A61K31/513 , A61K31/555 , A61K31/4745 , A61K31/7072 , A61K2039/50520130101 , A61K39/3955 , C07K16/2818 , C07K16/2827
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公开(公告)号：EP3811931B1
公开(公告)日：2024-07-03
申请号：EP19823228.2
申请日：2019-06-20
IPC: A61K9/127 , A61K31/404 , A61K31/4745 , A61K31/704 , A61K47/04 , A61K47/24 , A61K47/28 , A61P35/00
CPC classification number: A61K31/4745 , A61K31/404 , A61P35/00 , A61K31/704 , A61K47/28 , A61K45/06 , C07K16/2827 , A61K39/39558 , A61K2039/50520130101 , A61K9/1271 , A61K9/1277
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公开(公告)号：EP4380982A1
公开(公告)日：2024-06-12
申请号：EP22782792.0
申请日：2022-08-05
Applicant: Xencor, Inc.
Inventor： HICKINGBOTTOM, Barbara , FOSTER, Paul , CLYNES, Raphael , DING, Ying , BAO, Lei , AVERSA-FLEENER, Catherine
CPC classification number: C07K2317/3120130101 , A61P35/00 , A61K2039/50520130101 , C07K16/2827 , C07K16/468 , C07K16/3069 , C07K16/2818 , C07K16/2896 , C07K2317/5520130101 , A61K31/337 , A61K31/555 , A61K31/573
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公开(公告)号：EP4370553A1
公开(公告)日：2024-05-22
申请号：EP22764585.0
申请日：2022-07-13
Applicant: GENENTECH, INC.
Inventor： GAMPA, Gautham , HOSSEINI, Iraj , HUSENI, Mahrukh , KOERBER, James, Thomas , PAYANDEH, Jian, Mehr-dean , RUTZ, Sascha , SUN, Yonglian , CHIU, Cecilia, Pui Chi , DELFINO, Teresita, Arenzana
CPC classification number: C07K16/2866 , C07K2317/3320130101 , C07K2317/7620130101 , C07K2317/9220130101 , C07K2317/2420130101 , C07K2317/73220130101 , C07K2317/4120130101 , A61K2039/50720130101 , C07K16/2827 , A61P35/00
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公开(公告)号：EP4370155A1
公开(公告)日：2024-05-22
申请号：EP22842996.5
申请日：2022-07-06
Applicant: MacroGenics, Inc.
Inventor： ZHOU, Yan , SAMPATHKUMAR, Krishnan , BURKE, Stephen James , WANG, Xiaoyan
IPC: A61K39/395 , A61K45/06 , A61P35/00
CPC classification number: A61P35/00 , A61K45/06 , C07K16/2827 , A61K39/39591 , C07K2317/2420130101
