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公开(公告)号:EP4433493A1
公开(公告)日:2024-09-25
申请号:EP22818763.9
申请日:2022-11-21
Applicant: Enantis s.r.o.
Inventor: CHALOUPKOVA, Radka , STEPANKOVA, Veronika , HORACKOVA, Aneta , BEDNAR, David , KUTALKOVA, Katerina , LASKOVA, Veronika
IPC: C07K14/475
CPC classification number: C07K14/50 , C07K2319/2120130101 , C07K2319/5020130101 , A61K38/00 , A61K8/64 , A61Q19/00 , A61K2800/1020130101
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公开(公告)号:EP4426332A1
公开(公告)日:2024-09-11
申请号:EP22890952.9
申请日:2022-10-28
Applicant: Navicure Biopharmaceuticals Limited
Inventor: WU, Chia-Mao
IPC: A61K38/17 , A61K38/16 , C07K14/705 , C07K14/21 , C07K14/18
CPC classification number: C07K2319/5020130101 , C07K2319/0120130101 , C07K14/525 , C12N15/62 , C07K14/005 , C12N2710/1203420130101 , C12N2710/1202220130101 , A61K39/12 , A61P31/00 , A61K2039/5556620130101 , A61K2039/57520130101 , C12N2770/2403420130101
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公开(公告)号:EP4423267A1
公开(公告)日:2024-09-04
申请号:EP22888501.8
申请日:2022-10-27
Inventor: LIN, Michael Z. , ZOU, Xinzhi , CHUNG, Hokyung
IPC: C12N15/11 , C12N7/01 , C07K14/47 , C12N15/861
CPC classification number: C07K14/4702 , C07K2319/0020130101 , C07K2319/0220130101 , C07K2319/5020130101 , C12N9/48 , C12N15/625 , C07K14/535 , C07K14/71 , C07K2319/0320130101 , C12N15/86 , C12N2760/2024320130101 , C12N2760/2023220130101 , A61K35/768 , C12N2770/2422220130101
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公开(公告)号:EP4416281A1
公开(公告)日:2024-08-21
申请号:EP22880475.3
申请日:2022-10-14
Applicant: Pannon Egyetem
Inventor: JÁRVÁS, Gábor , SZIGETI, Márton Géza , JANKOVICS, Hajnalka , KOVÁCS, Noémi , FARSANG, Róbert
CPC classification number: C07K2319/2020130101 , C07K2319/2120130101 , C07K2319/5020130101 , C12N9/2402 , C12N11/00 , C12N15/70 , C12Y302/01
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公开(公告)号:EP4353750A3
公开(公告)日:2024-07-24
申请号:EP23220747.2
申请日:2016-12-22
Applicant: iCell Gene Therapeutics LLC
Inventor: MA, Yupo , PINZ, Kevin , JIANG, Xun , WADA, Masayuki , CHEN, Kevin
CPC classification number: C07K16/28 , A61P35/00 , A61K2039/50520130101 , A61P37/06 , A61P35/02 , A61K38/00 , C07K14/5443 , C07K14/7051 , C07K14/70517 , C07K14/70578 , C07K16/2803 , C07K16/2812 , C07K16/2866 , C07K16/2887 , C07K16/289 , C07K16/2896 , C07K2317/62220130101 , C07K2319/0220130101 , C07K2319/0320130101 , C07K2319/7420130101 , C07K2319/5020130101 , A61K2239/2220230501 , A61K2239/5720230501 , A61K39/4613 , A61K39/464471 , C12N5/0636 , A61K39/464419 , A61K39/4632 , A61K39/4644 , A61K39/4631 , C12N5/0646 , A61K39/4611
Abstract: The present disclosure relates to compositions and methods relating to chimeric antigen receptor (CAR) polypeptides and methods relating thereto. In one embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides directed to at least two targets. In another embodiment, the present disclosure relates to engineered cells having chimeric antigen receptor polypeptides and an enhancer moiety.
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公开(公告)号:EP4399299A1
公开(公告)日:2024-07-17
申请号:EP22868284.5
申请日:2022-09-07
Applicant: Metagenomi, Inc.
Inventor: THOMAS, Brian C. , BROWN, Christopher , GOLTSMAN, Daniela S.A. , LAPERRIERE, Sarah , CASTELLE, Cindy , ALEXANDER, Lisa , CHIU, Mary Kaitlyn , TEMOCHE-DIAZ, Morayma , THOMAS, Anu
CPC classification number: C12N15/90 , C12N15/70 , C12N9/22 , C12N15/1096 , C12N2800/9020130101 , C12N9/1276 , C12Y207/07049 , C07K2319/8120130101 , C07K2319/2120130101 , C07K14/005 , C07K2319/5020130101 , C12N2795/1812220130101
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公开(公告)号:EP4387649A1
公开(公告)日:2024-06-26
申请号:EP22859046.9
申请日:2022-08-16
Applicant: WEREWOLF THERAPEUTICS, INC.
Inventor: WINSTON, William , HICKLIN, Daniel , SALMERON-GARCIA, Jose Andres , SEIDEL-DUGAN, Cynthia , BRODKIN, Heather , STEINER, Philipp
IPC: A61K38/20 , A61K38/21 , A61K39/395 , A61P35/00 , C07K14/54 , C07K14/555
CPC classification number: A61K38/21 , A61P35/00 , C07K14/555 , A61K2039/50520130101 , C07K16/2818 , A61K39/3955 , C07K14/55 , C07K14/5434 , C07K2319/3120130101 , C07K2319/3020130101 , C07K2319/5020130101 , A61K38/2013 , A61K38/208 , A61K9/0019
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公开(公告)号:EP4373862A1
公开(公告)日:2024-05-29
申请号:EP22845886.5
申请日:2022-07-15
Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
Inventor: CHICHILI, Vishnu Priyanka Reddy , NAMBU, Takeru , IGAWA, Tomoyuki , YAMAMOTO, Yohei , SATO, Motohiko , HIRONIWA, NAOKA
CPC classification number: C12N15/1058 , C40B40/08 , C07K2319/5020130101 , C07K14/5434 , C07K16/244 , A61K2039/50520130101 , A61P35/00 , C07K2317/5620130101 , C07K2317/9220130101 , C07K2317/9420130101
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公开(公告)号:EP4359443A2
公开(公告)日:2024-05-01
申请号:EP22829365.0
申请日:2022-06-24
Applicant: Harpoon Therapeutics, Inc.
Inventor: WESCHE, Holger , LIN, Shuoyen Jack , KWANT, Kathryn , LEMON, Bryan D. , AUSTIN, Richard J.
IPC: C07K16/28 , C07K14/725 , C07K14/765 , A61P35/00
CPC classification number: A61K47/64 , C07K2319/5020130101 , C07K7/06 , C07K2319/0220130101 , C07K2319/2120130101 , C07K2319/3020130101 , C07K2319/0020130101 , C07K16/468 , C07K2317/3120130101 , C07K2317/9420130101 , C07K2317/4020130101 , C07K2317/6220130101 , C07K2317/62220130101 , C07K16/18 , C07K16/2809 , C07K2319/3120130101 , C07K2319/3320130101 , C07K16/3069 , C07K16/30 , C07K16/2803 , C07K16/2863 , C07K2317/73220130101 , C07K2317/9220130101 , C07K16/2887 , C07K16/2878 , C07K16/28 , C07K2317/56520130101 , C07K2317/56920130101 , A61P35/00
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公开(公告)号:EP4441074A2
公开(公告)日:2024-10-09
申请号:EP22854318.7
申请日:2022-12-02
Inventor: LIU, David R. , CAHILL, Thomas J. III , DESOUZA, Philip , RAGURAM, Aditya , BANSKOTA, Samagya , AN, Meirui
IPC: C07K14/005 , C12N7/00 , C07K14/47 , C12N9/22 , C12N15/10 , C12N15/113 , C12N15/62 , C12N15/86
CPC classification number: C07K14/005 , C12N15/86 , C12N2740/1304520130101 , C12N2740/1302220130101 , C12N2740/1302320130101 , C12N9/22 , C12N15/102 , C12N15/1137 , C07K2319/09520130101 , C07K2319/03320130101 , C07K2319/5020130101 , C07K2319/73520130101 , C07K2319/0920130101 , C07K14/4713 , C12Y201/01037 , C12N2310/2020170501 , C12N15/113 , C12N15/1138