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公开(公告)号：EP3112862B1
公开(公告)日：2018-10-24
申请号：EP15754422.2
申请日：2015-02-27
Applicant: Sysmex Corporation
Inventor： KAWAI, Akinori
IPC: G01N33/493 , G01N21/49 , G01N21/64 , G01N33/48 , G01N33/483
CPC classification number: G01N21/6428 , G01N15/1434 , G01N21/49 , G01N21/6458 , G01N33/493 , G01N33/52 , G01N33/80 , G01N2015/0065 , G01N2021/6439 , G01N2201/06113
Abstract: The present invention relates to a method for analyzing urine sample, a reagent for analysis of urine sample and a reagent kit for analysis of urine sample, which are for detecting at least casts and erythrocytes as urinary particles.
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公开(公告)号：EP3384273A1
公开(公告)日：2018-10-10
申请号：EP16816219.6
申请日：2016-12-02
Applicant: Gothenburg Sensor Devices AB
Inventor： HÖÖK, Fredrik , BLOCK, Stephan , JOHANSSON FAST, Björn , LUNDGREN, Anders
CPC classification number: G01N15/1456 , B01L3/50273 , B01L2400/0463 , G01N2015/0065 , G01N2015/1006 , G01N2015/1087 , G01N2015/1493
Abstract: The disclosure relates to a method for determining a hydrodynamic size of an object, such as a nano-sized object, said method comprising the steps of: —providing a fluid interface, —linking said object to said fluid interface thereby providing a linked object, whereby the movement of said linked object is restricted by virtue of being linked to said fluid interface, —providing and determining a hydrodynamic shear force that acts on said linked object, —tracking the movement of said linked object, and —calculating the hydrodynamic size of the object using the Einstein-Smoluchowski relation.
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公开(公告)号：EP3371571A1
公开(公告)日：2018-09-12
申请号：EP16797769.3
申请日：2016-11-03
Applicant: Siemens Healthcare Diagnostics Products GmbH
Inventor： PRECHTL, Gottfried
IPC: G01N15/14
CPC classification number: G01N15/1434 , G01N15/06 , G01N15/1429 , G01N15/1459 , G01N2015/0065 , G01N2015/0687 , G01N2015/0693 , G01N2015/1006 , G01N2015/1402
Abstract: The invention relates to a method of detecting neutrophil extracellular traps in a sample (4) of a biofluid, wherein the sample (4) of the biofluid is supplied with a nucleic acid-selective dye, wherein, after the staining, a multitude of optical, particle-related measurements is determined in the sample (4) within the absorption range of the dye, in each case as a tuple of a measurement of a first optical feature and a second optical feature, wherein measurements of the first optical feature are selected within a sub-range (6) of all measured values of the first optical feature and those of the second optical feature within a sub-range (7) of all measured values of the second optical feature, and wherein the number of selected measurements for detection of the neutrophil extracellular traps is compared to a predetermined borderline value.
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公开(公告)号：EP3363913A1
公开(公告)日：2018-08-22
申请号：EP18156065.7
申请日：2018-02-09
Inventor： ALLIER, Cédric , BAQUE, Melissa , BORDY, Thomas , BOURDAT, Anne-Gaëlle , VELLOU, Daniel
IPC: C12Q1/68 , G01N33/487
CPC classification number: G01N15/0205 , C12Q1/6825 , C12Q1/6851 , G01N15/1468 , G01N21/272 , G01N21/4788 , G01N21/75 , G01N21/82 , G01N33/5304 , G01N2015/0057 , G01N2015/0065 , G01N2015/0092 , G01N2015/0222 , G01N2015/145 , G01N2021/755 , G03H2001/0447 , C12Q2525/301 , C12Q2563/137 , C12Q2565/301 , C12Q2565/607
Abstract: L'invention est un procédé de suivi de l'amplification d'une séquence de nucléotides dans un échantillon (10). L'échantillon est disposé entre une source de lumière (12) et un capteur d'image (16). Sous l'effet de réactifs d'amplification, mélangés à l'échantillon, une séquence de nucléotides, dite séquence cible, est répliquée de façon itérative, constituant une amplification de la séquence cible. Le procédé comporte l'acquisition d'une image représentative de la formation d'un précipité dans l'échantillon sous l'effet de l'amplification, à partir de laquelle on forme une image d'intérêt. L'application d'un indicateur statistique à l'image d'intérêt permet la détermination d'un indicateur d'amplification de la séquence cible.
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公开(公告)号：EP2889603B1
公开(公告)日：2018-08-01
申请号：EP13846617.2
申请日：2013-08-30
Applicant: Sony Corporation
Inventor： TAKEUCHI Taichi , IMANISHI Shingo
CPC classification number: G01N15/1436 , G01N15/1429 , G01N15/1434 , G01N15/1459 , G01N21/21 , G01N21/47 , G01N21/49 , G01N21/53 , G01N21/645 , G01N2015/0065 , G01N2015/1006 , G01N2021/6478 , G01N2201/06113 , G01N2201/0638 , G01N2201/0683
Abstract: A microparticle measuring apparatus for highly accurately detecting the position of a microparticle flowing through a flow channel includes a light irradiation unit for irradiating a microparticle flowing through a flow channel with light, and a scattered light detection unit for detecting scattered light from the microparticle, including an objective lens for collecting light from the microparticle, a light splitting element for dividing the scattered light from the light collected by the objective lens, into first and second scattered light, a first scattered light detector for receiving an S-polarized light component, and an astigmatic element disposed between the light splitting element and the first scattered light detector, and making the first scattered light astigmatic. A relationship between a length L from a rear principal point of the objective lens to a front principal point of the astigmatic element, and a focal length f of the astigmatic element satisfies the following formula I. 1.5 �¢ f ‰¤ L ‰¤ 2.5 �¢ f
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6.发明授权
公开(公告)号：EP3027011B1
公开(公告)日：2018-07-04
申请号：EP14747165.0
申请日：2014-07-22
Applicant: DeLaval Holding AB
Inventor： FOLKESSON, Johan , JÖNSSON, Patrik , NILSSON, Lars , PERSSON, Örjan
CPC classification number: G01N33/04 , G01N1/38 , G01N1/4077 , G01N15/06 , G01N15/10 , G01N35/1095 , G01N2015/0065 , G01N2015/008 , G01N2015/0693 , G01N2015/1062
Abstract: A method for and a device to be used when preparing a milk sample that contains a first constituent and a second constituent. The device includes a first section (1), a second section (2), a third section (3) and fourth section (4). The milk sample is centrifuged to obtain a plurality of sample parts including a first sample part of a first volume, in which first sample part the first constituent is contained, and a second sample part of a second volume, in which second sample part the second constituent is contained. A solution is provided and supplied to the device. At least one of the sample parts is removed from the milk sample. A remaining sample part and the solution are mixed to form a sample mixture in which the remaining sample part is distributed. The sample mixture is discharged from the device.
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7.发明公开
公开(公告)号：EP3156477A4
公开(公告)日：2018-06-13
申请号：EP14895042
申请日：2014-06-16
Applicant: NIKON CORP
Inventor： KIYOTA YASUJIRO , KII HIROAKI
CPC classification number: G01N33/4833 , C12M41/36 , C12M41/48 , C12Q1/02 , G01N15/0227 , G01N15/06 , G01N2015/0065 , G01N2015/0277 , G01N2015/0693 , G02B21/02 , G02B21/36 , G06K9/0014 , G06K9/00147 , G06T7/0012 , G06T2207/10056 , G06T2207/30024 , G06T2207/30242
Abstract: An observation apparatus includes: an area calculation unit that calculates a colony area based on an image in which a cell colony is captured; a cell number calculation unit that calculates, based on the image, the number of cells included in a target colony of which an area is calculated by the area calculation unit; and a density calculation unit that calculates, based on the area of the target colony calculated by the area calculation unit and the number of the cells included in the target colony calculated by the cell number calculation unit, a density of the cells included in the target colony.
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公开(公告)号：EP3123176A4
公开(公告)日：2018-04-25
申请号：EP15768543
申请日：2015-03-23
Applicant: UNIV COLORADO REGENTS
Inventor： WAGNER DAVID
IPC: G01N33/68 , A61K31/00 , G01N33/569
CPC classification number: G01N33/6896 , A61K31/00 , G01N15/14 , G01N33/56972 , G01N33/6893 , G01N2015/0065 , G01N2015/1006 , G01N2333/70578 , G01N2333/70596 , G01N2800/042 , G01N2800/285 , G01N2800/50 , G01N2800/52 , G01N2800/54 , G01N2800/56
Abstract: Cellular markers useful for methods of diagnosing multiple sclerosis (MS), relapse of MS patients and disease progression in MS patients, as well as identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS). Methods of differential diagnosis of patients presenting with clinically isolated syndrome (CIS) suggestive of MS and/or Radiologically Isolated Syndrome (RIS) for presence of MS or relapse of MS, or lack thereof. Methods of treating patients having multiple sclerosis.
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9.发明公开URINALYSIS SYSTEM, IMAGE-CAPTURING DEVICE, CELL IMAGE-CAPTURING DEVICE, URINALYSIS METHOD, MANAGEMENT DEVICE, AND INFORMATION PROCESSING METHOD 审中-公开尿分析系统，图像捕获装置，细胞图像捕获装置，尿分析方法，管理装置和信息处理方法
公开(公告)号：EP3279657A1
公开(公告)日：2018-02-07
申请号：EP16771866.7
申请日：2016-01-29
Applicant: Sysmex Corporation
Inventor： FUKUDA,Masakazu , TANAKA, Masamichi , TANAKA, Yousuke
IPC: G01N33/493 , G01N15/14 , G01N21/78 , G01N33/483 , G01N33/52
CPC classification number: G01N15/1463 , G01N1/14 , G01N15/14 , G01N15/1436 , G01N15/1459 , G01N21/6428 , G01N21/78 , G01N33/483 , G01N33/48792 , G01N33/493 , G01N33/52 , G01N2015/0065 , G01N2015/1006 , G01N2021/6439 , G01N2201/068
Abstract: A urine analysis system 10 includes: a testing apparatus 10 that measures particles included in a urine sample according to a flow cytometry method; an image capturing apparatus 20 that captures images of particles in the urine sample to acquire cell images; and a management apparatus 30 that receives a measurement result obtained by the testing apparatus 10 and the cell images acquired by the image capturing apparatus 20. The management apparatus 30 generates an order to capture an image of the urine sample based on the measurement result obtained by the testing apparatus 10. The image capturing apparatus 20 executes the image capturing processing of the particles in the urine sample for which the image capturing order has been generated by the management apparatus 30, and transmits the acquired cell images to the management apparatus 30.
Abstract translation: 尿分析系统10包括：根据流式细胞术方法测量包含在尿样中的颗粒的测试装置10; 图像捕获装置20，其捕获尿样中的颗粒的图像以获取细胞图像; 以及管理装置30，其接收由测试装置10获得的测量结果和由图像捕获装置20获取的细胞图像。管理装置30基于由以下获得的测量结果来生成捕获尿样的图像的指令： 检查装置10.摄像装置20执行由管理装置30生成了摄影顺序的尿样中的粒子的摄像处理，并将所获取的细胞图像发送给管理装置30。
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10.发明授权
公开(公告)号：EP2264430B1
公开(公告)日：2018-01-10
申请号：EP10182264.1
申请日：2000-11-29
Applicant: XY, LLC
Inventor： Buchanan, Kristopher S. , Herickhoff, Lisa
CPC classification number: G01N15/1404 , G01N2015/0065 , G01N2015/1006 , G01N2015/1409 , G01N2015/1413 , G01N2015/1415 , G01N2015/149 , Y10T436/101666
Abstract: An improved nozzle system for a flow cytometer have been invented for a high efficiency orientation and sorting process of a flat sample and dedicates items such as equine or bovine sperm cells. This improved nozzle system comprises a nozzle (16) with a novel interior surface geometry that can both gently accelerate the cells and can include an elliptical-like, single torsional interior surface element within (c) the nozzle, i.e., a single torsional orientation nozzle (6). The elliptical-like, single torsional interior surface element (e.g.) (8, 9, 10) may have a laminar flow surface and may produce the simplest flow path for applying minimal forces which act in either an accelerative nature or orienting hydrodynamic forces, namely, the single torsional orientation forces, to orient a flat sample (16) such as animal sperm cells into a proper direction for an analyzing and efficiently sorting process in clinical use, for research and for the animal insemination industry.
