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1.发明公开
公开(公告)号：EP4461808A2
公开(公告)日：2024-11-13
申请号：EP24189199.3
申请日：2014-03-14
申请人： DiscGenics, Inc.
IPC分类号： C12N5/0775
摘要： The present disclosure relates to discogenic cell populations, methods of deriving, and methods of using them. The presently described discogenic cell populations may be used to restore or regenerate damaged, diseased, or missing intervertebral discs of a subject. The presently described discogenic cell populations can be derived from and administered or implanted into a subject, or may be derived from an unrelated donor.
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公开(公告)号：EP4460563A2
公开(公告)日：2024-11-13
申请号：EP23737539.9
申请日：2023-01-04
申请人： Ronawk, Inc.
发明人： MELLOTT, Adam J.
IPC分类号： C12N5/16 , C12N5/0735 , C12N5/0775 , C12N15/86 , C12N15/87 , C07K17/02
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公开(公告)号：EP4458349A1
公开(公告)日：2024-11-06
申请号：EP22915868.8
申请日：2022-12-21
发明人： TAN Zheli
IPC分类号： A61K9/127 , A61K35/12 , A61K47/69 , A61P11/00 , A61P43/00 , C12N5/0735 , C12N5/0775 , C12N5/10 , C12N15/09
摘要： An exosome comprising at least one exosome marker protein selected from among CD63, CD81 and CD9, and an integrin α and/or an integrin β in a lipid bilayer is disclosed. This exosome allows drug delivery with high target selectivity.
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公开(公告)号：EP4440597A1
公开(公告)日：2024-10-09
申请号：EP22902365.0
申请日：2022-11-30
发明人： SEGAL, Benjamin , SAS, Andrew , JEROME, Andrew , LIU, Tom
IPC分类号： A61K38/18 , C12N5/0775 , C12N5/0735 , C12N5/078
CPC分类号： C12N5/0642 , C12N5/0647 , C12N2501/230420130101 , C12N2501/2220130101 , C12N2510/0020130101 , C12N2502/08520130101 , A61K35/15 , C12N2500/2520130101 , C12N2501/1520130101 , C12N2502/117120130101 , C12N2501/23120130101 , C12N2501/2020130101 , A61K48/00 , A61K9/0048 , A61K9/0019 , C12N2750/1414320130101 , C12N2740/1604320130101 , A61K35/51 , A61K35/28 , A61P21/00
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5.发明公开
公开(公告)号：EP4440584A1
公开(公告)日：2024-10-09
申请号：EP22865897.7
申请日：2022-11-25
申请人： Celligenics Pte Ltd.
发明人： YEO, Aimin , MOK, Pamela , CHEN, Sixun , AW, Yi Bing
IPC分类号： A61K35/28 , C12N5/0775 , C07K14/535 , C07K14/705 , A61K35/51 , A61P17/02
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公开(公告)号：EP4438721A2
公开(公告)日：2024-10-02
申请号：EP24190629.6
申请日：2008-03-21
IPC分类号： C12N5/0775
CPC分类号： A61K35/28 , A61K2035/12220130101 , A61K2035/12420130101 , C12N5/0663 , A61P11/00
摘要： Methods of treating autoimmune diseases, allergic responses, cancer, inflammatory diseases, or fibrosis in an animal, promoting would healing, repairing epithelial damage and promoting angiogenesis in an organ or tissue of an animal by administering to the animal mesenchymal stem cells in an effective amount.
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7.发明公开
公开(公告)号：EP4426322A1
公开(公告)日：2024-09-11
申请号：EP22888289.0
申请日：2022-10-31
IPC分类号： A61K35/28 , C12N5/0775 , A61K35/24 , A61P35/00
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公开(公告)号：EP4410297A1
公开(公告)日：2024-08-07
申请号：EP21958020.6
申请日：2021-09-27
发明人： CHU, Li-Li
IPC分类号： A61K35/50 , C12N5/0775
CPC分类号： C12N5/0668 , C12N2500/9920130101 , C12N2501/2420130101 , C12N2501/2520130101 , A61K35/28
摘要： Provided in the present invention are a decidual placental mesenchymal stem cell and a culture method therefor. The method comprises: in an existing culture method for a mesenchymal stem cell, an induction step is added, so that the decidual placental mesenchymal stem cell highly expresses Decoy receptor 3 (DcR3). Further provided in the present invention is the use of the decidual placental mesenchymal stem cell in the preparation of a drug for promoting angiogenesis.
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公开(公告)号：EP4408979A1
公开(公告)日：2024-08-07
申请号：EP21810715.9
申请日：2021-09-30
IPC分类号： C12N5/0775 , C12Q1/6881 , C07K14/47 , G01N33/50
CPC分类号： C12N5/0667 , C12Q1/6881 , C07K14/47 , G01N33/574 , C12Q1/6886 , C12Q2600/15820130101
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公开(公告)号：EP4405463A1
公开(公告)日：2024-07-31
申请号：EP22814265.9
申请日：2022-10-14
申请人： Lonza Sales AG
IPC分类号： C12N5/0775 , C12N9/00 , C12N15/09 , C12N15/63
CPC分类号： C12N5/0667 , A61K35/12 , C12N15/113 , C12N15/87 , C12N2310/1420130101 , C12N2320/1220130101 , C12N2330/3120130101 , A61K31/366 , A61K31/713 , A61K31/505
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