公开(公告)号：EP3524958B1

公开(公告)日：2024-09-25

申请号：EP18211011.4

申请日：2008-11-25

IPC分类号： G01N1/18 ,  G01N33/82

CPC分类号： G01N33/82 ,  Y10T436/20 ,  Y10T436/203332 ,  Y10T436/24 ,  Y10T436/10

公开(公告)号：EP3411011B1

公开(公告)日：2024-09-18

申请号：EP17748282.5

申请日：2017-02-03

IPC分类号： A61K8/60 ,  A61K8/36 ,  A61K8/67 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61K8/99 ,  A61K31/714 ,  A61K35/74 ,  C12Q1/04 ,  G01N33/82 ,  A61P17/10

CPC分类号： A61Q19/00 ,  A61K8/606 ,  A61Q19/08 ,  A61K8/99 ,  A61K31/714 ,  C12Q1/04 ,  G01N33/82 ,  A61K2800/8120130101 ,  G01N2800/2020130101 ,  A61K35/74 ,  A61P17/10

公开(公告)号：EP4414709A1

公开(公告)日：2024-08-14

申请号：EP22878706.5

申请日：2022-08-11

申请人： Innobation Bio Co., Ltd.

发明人： KIM, Seung Ku ,  KIM, Ki Tae

IPC分类号： G01N33/574 ,  G01N33/82 ,  G01N33/92 ,  G01N33/68 ,  G01N30/72

CPC分类号： G01N33/92 ,  G01N33/82 ,  G01N30/72 ,  G01N33/68 ,  G01N33/574

摘要： The present invention relates to biomarkers for cancer diagnosis and uses thereof, and more particularly to a composition for diagnosing or predicting cancer prognosis, comprising an agent for measuring levels of at least two biomarkers selected from the group consisting of Complement Component 7 (C7), Dodecanoyl-L-carnitine (DC), Lysophosphatidylcholine (LPC), Histidine-Rich Glycoprotein (HRG) and Osteopontin in blood, and a method of using the biomarker to provide information about the diagnosis or prognosis of cancer.
In the present invention, it was confirmed that the level of complement component 7 (C7), dodecanoyl-L-carnitine (DC), lysophosphatidylcholine (LPC), histidine-rich glycoprotein (HRG), and/or osteopontin (OPN) in blood of lung and/or hepatic cancer patients has been found to have different patterns than that of normal individuals, and the combination of these markers has been shown to improve the diagnosis of various cancers, including lung or hepatic cancer. Accordingly, the biomarkers of the present invention can be useful in cancer diagnosis and prognosis.

公开(公告)号：EP4379384A2

公开(公告)日：2024-06-05

申请号：EP24164757.7

申请日：2020-01-15

申请人： Siemens Healthcare Diagnostics Inc.

发明人： WEI, Tie ,  LI, Jie ,  YUE, Yun

IPC分类号： G01N33/82

CPC分类号： B01L3/502761 ,  B01L2200/1620130101 ,  B01L2300/08720130101 ,  B01L3/502715 ,  C12Q1/44 ,  G01N33/92 ,  G01N33/82 ,  G01N33/743 ,  G01N2333/9220130101 ,  G01N33/54393

摘要： Methods of mitigating lipoprotein interference in in vitro diagnostic assays for target hydrophobic analytes are disclosed, as well as compositions, kits, and devices useful in said methods. A pretreatment reagent is utilized that includes at least one enzyme that digests lipoprotein.

公开(公告)号：EP3645998B1

公开(公告)日：2023-11-15

申请号：EP18823246.6

申请日：2018-06-26

发明人： Mendoza, Estevan

IPC分类号： G01N1/28 ,  G01N33/483 ,  G01N33/487 ,  G01N33/49 ,  G01N33/50 ,  G01N33/53 ,  G01N33/82 ,  G01N33/98 ,  G01N35/00 ,  G01N37/00 ,  B01L3/00 ,  G01N1/40 ,  G01N33/543 ,  G01N33/558 ,  G01N35/10

公开(公告)号：EP3152185B1

公开(公告)日：2023-10-04

申请号：EP15725061.4

申请日：2015-06-01

发明人： KOBOLD, Uwe ,  THIELE, Roland ,  WEISS, Noah ,  BROWN, Lauren

IPC分类号： G01N27/623 ,  G01N33/82 ,  G01N33/487

公开(公告)号：EP4222502A1

公开(公告)日：2023-08-09

申请号：EP21783252.6

申请日：2021-09-27

申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

发明人： BAECHER, Silvia ,  GEISTANGER, Andrea ,  GRUBER, Dominik ,  JOSEL, Hans-Peter

IPC分类号： G01N33/82

公开(公告)号：EP3359200B1

公开(公告)日：2023-08-02

申请号：EP16854239.7

申请日：2016-10-05

发明人： BORRELLI, Joseph ,  TANG, Liping ,  ZHOU, Jun

IPC分类号： A61K47/36 ,  A61K31/728 ,  C08B37/08 ,  C08J3/075 ,  G01N33/82 ,  A61K49/00 ,  G01N33/68 ,  A61K47/55 ,  A61K47/69 ,  A61K38/18 ,  A61K38/19 ,  A61P19/00

公开(公告)号：EP3401681B1

公开(公告)日：2023-03-29

申请号：EP18168500.9

申请日：2018-04-20

发明人： CHOI, Euiyul ,  JOO, Hoodon ,  KIM, Jinsu

IPC分类号： G01N33/558 ,  G01N33/68 ,  G01N33/82

公开(公告)号：EP3973290A1

公开(公告)日：2022-03-30

申请号：EP20730516.0

申请日：2020-05-14

申请人： ProciseDx Inc.

发明人： ZHOU, Jinyao ,  HALE, Michael ,  WESTIN, Stefan ,  RENSHAW, Mark ,  MIMMS, Larry ,  REDDY, Rukmini ,  SRIKRISHNAN, Raj

IPC分类号： G01N33/542 ,  G01N33/82