公开(公告)号：JP2014166980A

公开(公告)日：2014-09-11

申请号：JP2013216605

申请日：2013-10-17

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： YAMASHITA AKIRA ,  NISHIMURA SEIJIRO ,  NAGAHAMA HISASHI

IPC: C07D307/08 ,  C07B61/00

CPC classification number: C07D307/08

Abstract: PROBLEM TO BE SOLVED: To provide an industrially advantageous method of manufacturing tetrahydrofuran from 1,4-butanediol by using an acid catalyst, which can suppress reduction of reaction rate and a production amount of a solid by-product, and stably achieve high productivity.SOLUTION: There is provided a method of manufacturing tetrahydrofuran having a water concentration in a reactor liquid phase of 1.4 to 10 wt.% by supplying 1,4-butanediol to a reaction vessel and conducting a cyclodehydration reaction in the presence of an acid catalyst.

Abstract translation: 要解决的问题：通过使用能够抑制反应速度的降低和固体副产物的产生量的酸催化剂，提供从1,4-丁二醇制造四氢呋喃的工业上有利的方法，并且稳定地实现高生产率。 解决方案：提供了通过向反应容器中加入1,4-丁二醇并在酸催化剂存在下进行环化脱水反应制备四氢呋喃的方法，其中反应器液相中的水浓度为1.4至10重量％。

公开(公告)号：JP2011162780A

公开(公告)日：2011-08-25

申请号：JP2011006015

申请日：2011-01-14

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： YAMASHITA AKIRA ,  KUZUMI EMI ,  UTSUNOMIYA MASARU ,  NISHIMURA SEIJIRO

IPC: C08G65/20

Abstract: PROBLEM TO BE SOLVED: To provide a industrially profitable method for producing a polyether polyol improved in coloring without reducing producibility when the polyether polyol is obtained by performing a ring-opening polymerization reaction of a mixture of tetrahydrofuran and another cyclic ether copolymerizable with it in the presence of a catalyst. SOLUTION: In the method for producing the polyether polyol, a concentration of 1-5C ketones contained in another cyclic ether copolymerizable with the tetrahydrofuran is 500 wt.ppm or less. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 待解决的问题：提供一种工业上有利可图的生产聚醚多元醇的方法，其通过进行四氢呋喃和可与其共聚的其它环醚的混合物进行开环聚合反应而获得聚醚多元醇时，可以改善着色而不降低可生产性 它在催化剂存在下。 解决方案：在制备聚醚多元醇的方法中，与四氢呋喃可共聚的另一个环醚中含有的1-5C酮的浓度为500重量ppm以下。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2012250966A

公开(公告)日：2012-12-20

申请号：JP2011127241

申请日：2011-06-07

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： UTSUNOMIYA MASARU ,  YAMASHITA AKIRA ,  NISHIMURA SEIJIRO ,  TANAKA KOTA ,  HATTORI EIJI

IPC: C07D307/08 ,  B01J31/02 ,  C07B61/00

CPC classification number: Y02P20/52

Abstract: PROBLEM TO BE SOLVED: To provide an industrially advantageous manufacturing method for tetrahydrofuran comprising manufacturing tetrahydrofuran from 1,4-butanediol as a raw material using an acid catalyst having a pKa value of 4 or lower that permits avoidance of deposition of a solid byproduct to stably attain high productivity.SOLUTION: The manufacturing method for tetrahydrofuran comprises feeding 1,4-butanediol as a raw material into a reactor and carrying out a dehydrative cyclization reaction in the presence of an acid catalyst having a pKa value of 4 or lower to obtain tetrahydrofuran as a product, where the absorbance measured at one or more wavelengths selected within the measurement wavelength range of 650-750 nm is at least 0.01 and at most 3.0 based on the UV spectrum of the solution in the reactor.

Abstract translation: 解决的问题：提供工业上有利的四氢呋喃制造方法，其包括使用具有pKa值为4或更低的酸性催化剂的1,4-丁二醇作为原料制造四氢呋喃，其允许避免沉积固体 副产物稳定地获得高生产率。 解决方案：四氢呋喃的制造方法包括将1,4-丁二醇作为原料进料到反应器中，并在pKa值为4以下的酸催化剂存在下进行脱水环化反应，得到四氢呋喃 其中在650-750nm的测量波长范围内选择的一个或多个波长处测量的吸光度基于反应器中的溶液的UV光谱至少为0.01且至多为3.0。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2012236819A

公开(公告)日：2012-12-06

申请号：JP2012100209

申请日：2012-04-25

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： UTSUNOMIYA MASARU ,  TANAKA KOTA ,  YAMASHITA AKIRA ,  NISHIMURA SEIJIRO

IPC: C07D307/08 ,  C07B61/00

Abstract: PROBLEM TO BE SOLVED: To provide an industrially advantageous method for producing tetrahydrofuran by cyclodehydration reaction of 1,4-butanediol as a raw material, which can suppress reduction of reaction rate and stably achieve high productivity.SOLUTION: This production method of tetrahydrofuran comprises steps of: preparing a catalyst liquid by dissolving an acid with ≤4 pKa using 1,4-butanediol or tetrahydrofuran with 0.003-20.0 wt.% water content; preserving the catalyst liquid and thereafter, feeding the catalyst liquid to a reactor together with the raw material 1,4-butanediol; and conducting cyclodehydration reaction in the reactor to obtain tetrahydrofuran as the product.

Abstract translation: 待解决的问题：提供通过1,4-丁二醇作为原料的环化脱水反应生产四氢呋喃的工业上有利的方法，其可以抑制反应速率的降低并稳定地实现高生产率。 解决方案：该四氢呋喃的生产方法包括以下步骤：通过使用具有0.003-20.0重量％水含量的1,4-丁二醇或四氢呋喃溶解≤4pKa的酸来制备催化剂液体; 保存催化剂液体，然后将催化剂液体与原料1,4-丁二醇一起供给反应器; 并在反应器中进行环化脱水反应，得到四氢呋喃作为产物。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2012219066A

公开(公告)日：2012-11-12

申请号：JP2011087280

申请日：2011-04-11

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： UTSUNOMIYA MASARU ,  YAMASHITA AKIRA ,  NISHIMURA SEIJIRO ,  TANAKA KOTA ,  HATTORI EIJI

IPC: C07D307/08 ,  C07B61/00

Abstract: PROBLEM TO BE SOLVED: To provide a method of manufacturing tetrahydrofuran (THF) which reduces reduction of a reaction speed and the amount of solid by-products to be generated, can obtain stably high productivity and is advantageous industrially, regarding the method of manufacturing THF from 1,4-butanediol using an acid catalyst.SOLUTION: The method of manufacturing THF is characterized in that, when producing THF by supplying 1,4-butanediol of a raw material to a reaction tank and performing cyclodehydration reaction in the presence of sulfonic acid, a gas containing THF and water in the reaction tank is introduced into a heat exchanger and while supplying a part of a condensate obtained from an outlet of the heat exchanger to a gas phase part of the reaction tank, the remaining condensate is extracted to the outside of the reaction tank.

Abstract translation: 待解决的问题：为了提供减少反应速度的降低和产生的固体副产物的量的四氢呋喃（THF）的制造方法，可以获得稳定的高生产率并且在工业上是有利的，关于该方法 使用酸催化剂从1,4-丁二醇制造THF。 解决方案：制备THF的方法的特征在于，当通过向反应罐中加入原料的1,4-丁二醇制备THF并在磺酸存在下进行环化脱水反应时，含有THF和水的气体 将反应槽引入热交换器中，同时将从热交换器的出口获得的冷凝物的一部分供应到反应罐的气相部分，剩余的冷凝物被抽出到反应罐的外部。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2012172048A

公开(公告)日：2012-09-10

申请号：JP2011034969

申请日：2011-02-21

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： KONISHI NORIKAZU ,  YANO KAORI ,  UTSUNOMIYA MASARU ,  NISHIMURA SEIJIRO

IPC: C08G65/26

Abstract: PROBLEM TO BE SOLVED: To provide an industrially advantageous method for producing high-quality polyalkylene ether glycol with an excellent hue.SOLUTION: In the method for producing polyalkylene ether glycol, when the polyalkylene ether glycol is produced by ring-opening polymerization of a cyclic ether carried out in the presence of a carboxylic acid anhydride and a catalyst, absorbance in measurement of the carboxylic acid anhydride at one wavelength selected from measurement wavelength 300-330 nm based on a UV spectrum is ≤0.10.

Abstract translation: 待解决的问题：提供具有优异色调的高品质聚亚烷基二醇的工业上有利的方法。 解决方案：在聚亚烷基醚二醇的制备方法中，当通过在羧酸酐和催化剂存在下进行的环醚的开环聚合制备聚亚烷基醚二醇时，羧酸的测量中的吸光度 基于UV光谱，从测量波长300-330nm选择的一个波长的酸酐为≤0.10。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2013166918A

公开(公告)日：2013-08-29

申请号：JP2013002834

申请日：2013-01-10

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： ITO KANAKO ,  NISHIMURA SEIJIRO

IPC: C08G65/08 ,  C08G65/332

Abstract: PROBLEM TO BE SOLVED: To provide a polymerization method of a cyclic ether for stably obtaining a target product (polyoxyalkylene ether glycol) with the number average molecular weight of 500-4,000, which is useful for a material of an elastic fiber and a thermoplastic elastomer polyester elastomer, without producing any high molecular weight body in the start of a ring-opening polymerization reaction of the cyclic ether.SOLUTION: In a polymerization method of a cyclic ether, an ester of polyoxyalkylene ether glycol is obtained as a target product when ring-opening polymerization of a cyclic ether as a raw material is carried out in the presence of a carboxylic acid anhydride inside a polymerization reactor while using a ring-opening polymerization catalyst. In the polymerization method, the cyclic ether as a raw material and the ring-opening polymerization catalyst are supplied to the polymerization reactor while being prevented from mutual contact beforehand, and then, the ring-opening polymerization is started.

Abstract translation: 要解决的问题：提供用于稳定获得数均分子量为500-4,000的目标产物（聚氧化烯乙二醇）的环醚的聚合方法，其可用于弹性纤维和热塑性弹性体的材料 聚酯弹性体，在环状醚的开环聚合反应开始时不产生任何高分子量体。溶液：在环醚的聚合方法中，当环状聚合的聚氧亚烷基醚二醇的酯作为目标产物时获得 作为原料的环状醚的开环聚合在使用开环聚合催化剂的情况下，在聚合反应器内的羧酸酐的存在下进行。 在聚合方法中，将作为原料的环状醚和开环聚合催化剂预先供给到聚合反应器中，同时防止相互接触，然后开始开环聚合。

公开(公告)号：JP2010168321A

公开(公告)日：2010-08-05

申请号：JP2009013465

申请日：2009-01-23

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： UTSUNOMIYA MASARU ,  ASAKAWA KAORI ,  HATTORI EIJI ,  YAMASHITA AKIRA ,  NISHIMURA SEIJIRO

IPC: C07C67/303 ,  B01J23/44 ,  B01J23/755 ,  B01J27/236 ,  C07B61/00 ,  C07C69/16

CPC classification number: Y02P20/52

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing 1,4-diacetoxybutane in an improved yield without anxiety of clogging and contamination in higher efficiency by hydrogenating 1,4-diacetoxy-2-butene with suppressing amount of a by-product such as butyl acetate etc., formed without including a metal in a reaction solution. SOLUTION: The method for producing a hydrogenated ester includes previously bringing a catalyst containing a transition metal into contact with an inorganic base in hydrogenating an unsaturated ester in the presence of the catalyst to produce a corresponding hydrogenated ester. COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 待解决的问题：为了提供一种生产1,4-二乙酰氧基丁烷的方法，通过氢化1,4-二乙酰氧基-2-丁烯，抑制量的副产物，以更高的效率提高产率而不堵塞堵塞和污染的焦虑， 在反应溶液中形成不含有金属的产物如乙酸丁酯等。 解决方案：氢化酯的制备方法包括在催化剂存在下，使含有过渡金属的催化剂与无机碱接触，使不饱和酯氢化，生成相应的氢化酯。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2003026622A

公开(公告)日：2003-01-29

申请号：JP2001216789

申请日：2001-07-17

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： OKUBO KAZUYUKI ,  IWASAKA YOUJI ,  NISHIMURA SEIJIRO

IPC: C07C29/90 ,  C07B61/00 ,  C07C27/02 ,  C07C31/20 ,  C07C67/055 ,  C07C67/283 ,  C07C69/16

Abstract: PROBLEM TO BE SOLVED: To provide a method for stably carrying out a hydrogenation purification of a crude 1,4-butanediol obtained by distilling hydrolyzed solution and reacting butadiene with acetic acid and oxygen in the presence of a catalyst to produce a reaction product containing 1,4-diacetoxybutene, hydrogenating the reaction product, and hydrolyzing the hydrogenated product.
SOLUTION: The crude 1,4-butanediol having ≤0.5 wt.% concentration of 2-(4'-hydroxybutoxy)tetrahydrofuran based on the amount of the 1,4-butanediol is extracted from a lower part of a distillation column of a hydrolyzed liquid as a side stream, and the extracted crude 1,4-butanediol is subjected to the hydrogenation reaction.
COPYRIGHT: (C)2003,JPO

Abstract translation: 要解决的问题：提供一种在催化剂存在下，通过蒸馏水解溶液和使丁二烯与乙酸和氧反应得到的粗1,4-丁二醇的氢化纯化的方法，以产生含有1 ，4-二乙酰氧基丁烯，氢化反应产物，并水解氢化产物。 解决方案：基于1,4-丁二醇的量，具有<= 0.5重量％浓度的2-（4'-羟基丁氧基）四氢呋喃的粗1,4-丁二醇是从蒸馏塔的下部提取的 水解液体作为侧流，并将提取的粗1,4-丁二醇进行氢化反应。

公开(公告)号：JP2014139304A

公开(公告)日：2014-07-31

申请号：JP2013260400

申请日：2013-12-17

Applicant: Mitsubishi Chemicals Corp ,  三菱化学株式会社

Inventor： TANIGUCHI TAKANORI ,  KUZUMI EMI ,  NISHIMURA SEIJIRO

IPC: C08G65/26

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing a diester of a polyalkylene ether glycol capable of avoiding quality deterioration due to deterioration of hue and obtaining a colorless and transparent PTMG.SOLUTION: Provided is a method for producing a diester of a polyalkylene ether glycol wherein, when producing a diester of a polyalkylene ether glycol by ring-opening polymerization of a raw material cyclic ether in the presence of a catalyst, the ring-opening polymerization is conducted in the presence of 10-500 wt.ppm of an antioxidant relative to an amount of the raw material cyclic ether.

Abstract translation: 要解决的问题：提供一种聚亚烷基醚二醇的二酯的制备方法，其能够避免由于色相的劣化而导致的质量劣化，并获得无色透明的PTMG。提供了一种聚亚烷基醚的二酯的制备方法 二醇，其中当在催化剂存在下通过原料环醚的开环聚合制备聚亚烷基醚二醇的二酯时，开环聚合在10-500重量ppm的抗氧化剂存在下进行 相对于原料环醚的量。