公开(公告)号：US3716531A

公开(公告)日：1973-02-13

申请号：US3716531D

申请日：1968-10-31

申请人： SCHERING AG ,  SCHROEDER E ,  ALBRECHT R

发明人： ALBRECHT R ,  SCHRODER E ,  MUFTIC M

IPC分类号： C07D207/42 ,  C07D307/71 ,  C07D333/44 ,  C07D5/30

CPC分类号： C07D207/42 ,  C07D307/71 ,  C07D333/44

摘要： For combating and preventing infections caused by a variety of microbes such as bacteria and Trichomonas vaginalis, new compounds of the formula
WHEREIN X is O, S or NH; Y is O; S; -CH2-O-; -S-CH2-; -CH2-S-; -O-CH2-; -SO-; -SO-CH2-; CH2-SO-; -CH2-SO2-; -SO2-CH2- or -CA2-, A being H, methyl, ethyl or phenyl; and R1, R2 and R3 each represents alkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, alkoxyalkoxy, mono- or dialkylaminoalkyl, dialkylaminoalkoxy, amino, acylamino, mono- or dialkylamino, alkylsulfonylamino, acyloxy, alkylsulfonyloxy, benzyloxy groups wherein each alkyl, alkoxy or acyl residue is not more than five carbon atoms and acyl is derived from a carboxylic acid; halogen; or hydrogen with the provision that when Y represents -CH2-, at least one of R1, R2, and R3 is other than hydrogen.

摘要翻译： 为了防治由各种微生物（如细菌和阴道毛滴虫）引起的感染，式WHEREIN X的新化合物是O，S或NH; Y是O; S; -CH 2 -O-; -S-CH 2 - ; -CH 2 -S-; -O-CH 2 - ; -所以-; -SO-CH 2 - ; -CH 2 -SO-; -CH 2 -SO 2 - ; -SO 2 -CH 2 - 或-CA 2 - ，A为H，甲基，乙基或苯基; R1，R2和R3各自表示烷基，羟基，羟烷基，烷氧基，烷氧基烷基，烷氧基烷氧基，一或二烷基氨基烷基，二烷基氨基烷氧基，氨基，酰氨基，一烷基氨基或二烷基氨基，烷基磺酰氨基，酰氧基，烷基磺酰氧基，苄氧基，其中各烷基，烷氧基或 酰基残基不超过5个碳原子，酰基衍生自羧酸; 卤素; 或氢，条件是当Y表示-CH 2 - 时，R 1，R 2和R 3中的至少一个不是氢。