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22 条记录 (耗时 0.013 秒)

    Drug for hyperphospheremia and its preparative method
    4.
    发明授权
    Drug for hyperphospheremia and its preparative method 有权
    高脂血症药物及其制备方法

    公开(公告)号：US07662364B2

    公开(公告)日：2010-02-16

    申请号：US11576731

    申请日：2006-06-26

    申请人： Shi Biao Li ,  Min Qiao ,  Wei Sheng Zhang

    发明人： Shi Biao Li ,  Min Qiao ,  Wei Sheng Zhang

    IPC分类号： A61K31/74 ,  A61K31/7135

    CPC分类号： A61K33/24 ,  A61K31/795 ,  A61K31/80

    摘要： This invention reports a drug for hyperphospheremia and its preparative method. The preparation includes active constituents, lanthanum polystyrene sulfonate, and excipients. The preparative method in the invention can be summarized as follows: Polystyrene sulfonic acid is obtained by treating polystyrene sulfosalt with hydrochloric acid, soaked or eluted with water soluble lanthanum-contained solution, and washed with water till its PH is neutral. Then, the lanthanum polystyrene sulfonate solution is washed till the superfluous La− unexchanged is washed out. Lanthanum polystyrene sulfonate is taken out and crushed to powder after being dried. The lanthanum polystyrene sulfonate, whose weight percentage of lanthanum is 14-22%, is used as active constituents to prepare gastrointestinal tract preparations together with general amount of excipients with routine preparative method. In the invention, lanthanum polystyrene sulfonate is adopted as active constituents, mixed with excipients, and the preparation is obtained. It makes phosphate in alimentary tract become insoluble conjugates after gastrointestinal tract administration. The insoluble conjugates would be discharged. Thus, the drug can achieve the purpose of treating hyperphospheremia.

    摘要翻译： 本发明报道了高脂血症药物及其制备方法。 该制剂包括活性成分，聚苯乙烯磺酸镧和赋形剂。 本发明的制备方法可以概括如下：聚苯乙烯磺酸是用盐酸处理聚苯乙烯磺酸盐，用水溶性含镧溶液浸泡或洗脱得到的，用水洗涤至PH为中性。 然后，将聚苯乙烯磺酸镧溶液洗涤至多余的La-未改变被洗掉。 干燥后，将聚苯乙烯磺酸镧取出并粉碎成粉末。 作为活性成分，使用镧的重量百分比为14〜22％的聚苯乙烯磺酸镧与常规制备方法一起制备胃肠道制剂以及一般量的赋形剂。 在本发明中，采用聚苯乙烯磺酸镧作为活性成分，与赋形剂混合，得到制剂。 胃肠道给药后，使消化道磷酸盐变成不溶性结合物。 不溶性共轭物将被排出。 因此，该药物可以达到治疗高脂血症的目的。

    Drug for Hyperphospheremia and Its Preparative Method
    5.
    发明申请
    Drug for Hyperphospheremia and Its Preparative Method 有权
    高磷血症药物及其制备方法

    公开(公告)号：US20090016984A1

    公开(公告)日：2009-01-15

    申请号：US11576731

    申请日：2006-06-26

    申请人： Shi Biao Li ,  Min Qiao ,  Wei Sheng Zhang

    发明人： Shi Biao Li ,  Min Qiao ,  Wei Sheng Zhang

    IPC分类号： A61K31/795 ,  A61P3/00

    CPC分类号： A61K33/24 ,  A61K31/795 ,  A61K31/80

    摘要： This invention reports a drug for hyperphospheremia and its preparative method. The preparation includes active constituents, lanthanum polystyrene sulfonate, and excipients. The preparative method in the invention can be summarized as follows: Polystyrene sulfonic acid is obtained by treating polystyrene sulfosalt with hydrochloric acid, soaked or eluted with water soluble lanthanum-contained solution, and washed with water till its PH is neutral. Then, the lanthanum polystyrene sulfonate solution is washed till the superfluous La− unexchanged is washed out. Lanthanum polystyrene sulfonate is taken out and crushed to powder after being dried. The lanthanum polystyrene sulfonate, whose weight percentage of lanthanum is 14-22%, is used as active constituents to prepare gastrointestinal tract preparations together with general amount of excipients with routine preparative method. In the invention, lanthanum polystyrene sulfonate is adopted as active constituents, mixed with excipients, and the preparation is obtained. It makes phosphate in alimentary tract become insoluble conjugates after gastrointestinal tract administration. The insoluble conjugates would be discharged. Thus, the drug can achieve the purpose of treating hyperphospheremia.

    摘要翻译： 本发明报道了高脂血症药物及其制备方法。 该制剂包括活性成分，聚苯乙烯磺酸镧和赋形剂。 本发明的制备方法可以概括如下：聚苯乙烯磺酸是用盐酸处理聚苯乙烯磺酸盐，用水溶性含镧溶液浸泡或洗脱得到的，用水洗涤至PH为中性。 然后，将聚苯乙烯磺酸镧溶液洗涤至多余的La-未改变被洗掉。 干燥后，将聚苯乙烯磺酸镧取出并粉碎成粉末。 作为活性成分，使用镧的重量百分比为14〜22％的聚苯乙烯磺酸镧与常规制备方法一起制备胃肠道制剂以及一般量的赋形剂。 在本发明中，采用聚苯乙烯磺酸镧作为活性成分，与赋形剂混合，得到制剂。 胃肠道给药后，使消化道磷酸盐变成不溶性结合物。 不溶性共轭物将被排出。 因此，该药物可以达到治疗高脂血症的目的。

    Horizontal freezer with drawers
    8.
    发明授权
    Horizontal freezer with drawers 有权
    卧式冰柜带抽屉

    公开(公告)号：US06449976B1

    公开(公告)日：2002-09-17

    申请号：US09881094

    申请日：2001-06-15

    申请人： Yongsen Chai ,  Jian Ma ,  Biao Li ,  Kegang Huang

    发明人： Yongsen Chai ,  Jian Ma ,  Biao Li ,  Kegang Huang

    IPC分类号： F25D2502

    CPC分类号： F25D23/04 ,  A47B2210/01 ,  F25D11/022 ,  F25D23/026 ,  F25D23/061 ,  F25D25/025 ,  F25D2400/10

    摘要： A horizontal freezer comprising a housing including an upper freezing chamber and a freezing chamber, the upper freezing chamber and lower freezing chamber being separated by a plate, the upper freezing chamber having a top entrance and the lower freezing chamber having a side entrance; a cover connected to the top of the housing for closing the top entrance of the upper freezing chamber; a drawer being mounted in the lower freezing chamber by means of a sliding support assembly; an evaporator, at least part of which is embedded in said housing, the housing includes an upper front panel, back panel and two opposite side panels, with the upper front panel connected to the two opposite side panels. The sliding support assembly includes an inner sliding support and an outer sliding support.

    摘要翻译： 一种卧式冷冻机，包括：壳体，包括上部冷冻室和冷冻室，上部冷冻室和下部冷冻室由板分隔开，上部冷冻室具有顶部入口，下部冷冻室具有侧面入口; 盖子，连接到壳体的顶部，用于封闭上部冷冻室的顶部入口; 抽屉通过滑动支撑组件安装在下部冷冻室中; 蒸发器，其至少一部分嵌入所述壳体中，所述壳体包括上前面板，后面板和两个相对的侧板，其中所述上前面板连接到所述两个相对的侧板。 滑动支撑组件包括内部滑动支撑件和外部滑动支撑件。