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公开(公告)号:US20090226434A1
公开(公告)日:2009-09-10
申请号:US12321016
申请日:2009-01-15
申请人: Johannes Auer , Amy Berson , Dominique Christian Borie , Michael Brandt , Jose M. Lora , Stefan Ries
发明人: Johannes Auer , Amy Berson , Dominique Christian Borie , Michael Brandt , Jose M. Lora , Stefan Ries
IPC分类号: A61K39/395 , C07K16/18 , C12N5/16 , A61P37/06 , A61P37/02
CPC分类号: C07K16/2866 , A61K2039/505 , C07K2317/41 , C07K2317/565 , C07K2317/72 , C07K2317/732 , C07K2317/76
摘要: An antibody binding to CCR5 and being glycosylated with a sugar chain at Asn297, said antibody being characterized in that the amount of fucose within said sugar chain is 65% or lower has improved properties in anti-inflammatory therapy.
摘要翻译: 与CCR5结合并在Asn297处用糖链糖基化的抗体,所述抗体的特征在于所述糖链内的岩藻糖的量为65%以下具有改善的抗炎治疗性能。