公开(公告)号：US07884129B2

公开(公告)日：2011-02-08

申请号：US12124131

申请日：2008-05-20

申请人： Mi Rim Jin ,  Jae Ha Ryu ,  Hyoun Jeong Choi ,  Hyun Jin Jung ,  Kyoung Chul Park ,  Sun Young Kim

发明人： Mi Rim Jin ,  Jae Ha Ryu ,  Hyoun Jeong Choi ,  Hyun Jin Jung ,  Kyoung Chul Park ,  Sun Young Kim

IPC分类号： A01N43/08 ,  A61K39/00

CPC分类号： A61K36/42 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/343 ,  A23V2200/332

摘要： The present invention is related to an alcohol compound isolated from the extract of Cucurbitaceae family plant having anti-adipogenic and anti-obesity activity, and a composition comprising the same. The compound showed potent reducing activity of body weight, decreasing effect on the blood triglyceride and cholesterol level, activating activity of PPAR α and preventing activity from the adipogenesis of precursor fat cells with no toxicity, therefore, those extract can be useful in treating or preventing obesity and adipogenesis-involved diseases as a medicine or health care food.

摘要翻译： 本发明涉及从具有抗脂肪生成和抗肥胖活性的葫芦科家族植物提取物中分离的醇化合物和包含其的组合物。 该化合物显示出有效的体重降低活性，降低对血液甘油三酯和胆固醇水平的影响，激活PPARα的活性并预防前体脂肪细胞的脂肪形成的活性，无毒性，因此，这些提取物可用于治疗或预防 肥胖和脂肪生成涉及疾病作为医药或保健食品。

公开(公告)号：US20080280976A1

公开(公告)日：2008-11-13

申请号：US12124131

申请日：2008-05-20

申请人： Mi Rim JIN ,  Jae Ha RYU ,  Hyoun Jeong CHOI ,  Hyun Jin JUNG ,  Kyoung Chul PARK ,  Sun Young KIM

发明人： Mi Rim JIN ,  Jae Ha RYU ,  Hyoun Jeong CHOI ,  Hyun Jin JUNG ,  Kyoung Chul PARK ,  Sun Young KIM

IPC分类号： A61K31/343 ,  A61P3/00

CPC分类号： A61K36/42 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/343 ,  A23V2200/332

摘要： The present invention is related to an alcohol compound isolated from the extract of Cucurbitaceae family plant having anti-adipogenic and anti-obesity activity, and a composition comprising the same. The compound showed potent reducing activity of body weight, decreasing effect on the blood triglyceride and cholesterol level, activating activity of PPAR α and preventing activity from the adipogenesis of precursor fat cells with no toxicity, therefore, those extract can be useful in treating or preventing obesity and adipogenesis-involved diseases as a medicine or health care food.

摘要翻译： 本发明涉及从具有抗脂肪生成和抗肥胖活性的葫芦科家族植物提取物中分离的醇化合物和包含其的组合物。 该化合物显示出有效的体重减少活性，降低对血液甘油三酯和胆固醇水平的影响，激活PPARα的活性，并预防前体脂肪细胞脂肪形成的活性，无毒性，因此，这些提取物可用于治疗或预防 肥胖和脂肪生成涉及疾病作为医药或保健食品。