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公开(公告)号：US09993156B2
公开(公告)日：2018-06-12
申请号：US13879321
申请日：2010-10-14
申请人： Marcel Warntjes
发明人： Marcel Warntjes
CPC分类号： A61B5/0042 , A61B5/055 , G01R33/50 , G01R33/5608
摘要： A computerized method of generating a map of myelin tissue of a brain is described. In addition sub-maps of different myelin contents can be imaged. The method uses a simulation model comprising at least two interacting tissue compartments.
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公开(公告)号：US20140002076A1
公开(公告)日：2014-01-02
申请号：US13540027
申请日：2012-07-02
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G01R33/48
CPC分类号： G01R33/50 , G01R33/5614 , G01R33/5616 , G01R33/56341
摘要： Magnetic resonance imaging methods and apparatus for simultaneous measurement of the physical properties R1 and R2 relaxation rate, proton density, and apparent diffusion coefficient using a single magnetic resonance acquisition.
摘要翻译： 磁共振成像方法和装置，用于使用单个磁共振采集同时测量物理性质R1和R2松弛率，质子密度和表观扩散系数。
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公开(公告)号：US20110018537A1
公开(公告)日：2011-01-27
申请号：US12509022
申请日：2009-07-24
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G01R33/48
CPC分类号： G01R33/5602 , G01R33/50 , G01R33/5615 , G01R33/5616 , G01R33/5617
摘要： A magnetic resonance sequence includes an interleaved slice-selective pre-pulse and a slice-selective multi-echo acquisition. This sequence is repeated with different delays between the pre-pulse and the acquisition resulting in a matrix of complex images. Based on this matrix T1 and T2 relaxations, proton density and the B1 field can be estimated. These quantified parameters enable synthetic magnetic resonance imaging (MRI) and form a robust input for tissue segmentation in computer aided diagnosis for MRI.
摘要翻译： 磁共振序列包括交错切片选择性预脉冲和切片选择性多回波采集。 在预脉冲和采集之间以不同的延迟重复该序列，导致复杂图像的矩阵。 基于该矩阵T1和T2弛豫，可以估计质子密度和B1场。 这些量化的参数使得合成磁共振成像（MRI）并且在MRI的计算机辅助诊断中形成用于组织分割的鲁棒输入。
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公开(公告)号：US20100127704A1
公开(公告)日：2010-05-27
申请号：US12626705
申请日：2009-11-27
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G01R33/48
CPC分类号： G01R33/56 , G01R33/50 , G01R33/5608
摘要： A segmented MR image is provided by measuring a number of Magnetic Resonance Imaging parameters on an absolute scale. For example T1 relaxation, T2 relaxation and Proton Density PD can be measured on an absolute scale. The absolute values are then compared with known values for at least one type of tissue. For human tissue these parameters typically are in the order 300-4500 ms for T1, 50-1000 ms for T2 and 0-100% water for PD. Both T1 and T2 depend on the field strength. Based on a comparison between normal values for a particular type of tissue the values obtained for the image each pixel/voxel can be labeled with a certain probability that the voxel contains this type of tissue and segmented accordingly.
摘要翻译： 通过以绝对刻度测量多个磁共振成像参数来提供分段MR图像。 例如，T1弛豫，T2弛豫和质子密度PD可以以绝对尺度进行测量。 然后将绝对值与至少一种类型的组织的已知值进行比较。 对于人体组织，这些参数通常在T1为300-4500ms，T2为50-1000ms，PD为0-100％。 T1和T2都取决于场强。 基于特定类型的组织的正常值之间的比较，可以以一定概率标记图像获得的每个像素/体素的值，体素包含这种类型的组织并相应地分割。
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公开(公告)号：US08873822B2
公开(公告)日：2014-10-28
申请号：US13481918
申请日：2012-05-28
申请人： Marcel Warntjes
发明人： Marcel Warntjes
CPC分类号： G06T7/62 , G06T7/187 , G06T2207/10088 , G06T2207/20076 , G06T2207/30016
摘要： In a magnetic resonance imaging display system, the brain parenchymal fraction, a clinical measure for brain atrophy, is found by selection of white matter, grey matter, and/or cerebrospinal fluid based on quantitative magnetic resonance properties.
摘要翻译： 在磁共振成像显示系统中，通过基于定量磁共振性质的白质，灰质和/或脑脊髓液的选择来发现脑实质部分，脑部萎缩的临床措施。
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公开(公告)号：US20100103166A1
公开(公告)日：2010-04-29
申请号：US12521903
申请日：2007-12-21
申请人： Marcel Warntjes
发明人： Marcel Warntjes
CPC分类号： G06T7/0012 , A61B5/0037 , A61B5/0042 , A61B5/055 , A61B5/7445 , G01R33/5602 , G01R33/5608
摘要： In a method and a device MR images having various contrasts are scanned and then values for some or all of the parameters T1, T2 and PD related to the scanned MR images are determined. Based on the scanned MR images and the determined parameter values an initial conventional MR contrast image with some default scanner settings is generated, or alternatively, a stronger non-physical MR contrast image. The initial MR contrast image can then be manipulated by a user in response to movement of a user-controlled marker on a screen showing the contrast image such that a contrast optimized image can be obtained for a particular diagnosis in a very short time. Furthermore a quantitative image can be generated representing the amount of a single tissue type.
摘要翻译： 在方法和装置中扫描具有各种对比度的MR图像，然后确定与扫描的MR图像相关的一些或全部参数T1，T2和PD的值。 基于扫描的MR图像和确定的参数值，生成具有一些默认扫描仪设置的初始常规MR对比图像，或者替代地，更强的非物理MR对比图像。 响应于用户控制的标记在显示对比度图像的屏幕上的移动，用户可以操纵初始MR对比度图像，使得可以在非常短的时间内为特定诊断获得对比度优化的图像。 此外，可以生成表示单个组织类型的量的定量图像。
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公开(公告)号：US20090267945A1
公开(公告)日：2009-10-29
申请号：US12429321
申请日：2009-04-24
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G06T11/20
CPC分类号： G06T11/206 , A61B5/055 , A61B5/4869 , A61B5/4872 , A61B5/743 , G01R33/50 , G01R33/5608
摘要： In a magnetic resonance (MR) imaging display system, the values of at least two quantitative MR parameters for a given Region of Interest (ROI) are displayed and dynamically updated when the ROI is changed.
摘要翻译： 在磁共振（MR）成像显示系统中，当ROI被改变时，显示给定感兴趣区域（ROI）的至少两个定量MR参数的值并且动态地更新。
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8.发明授权公开(公告)号：US09618596B2
公开(公告)日：2017-04-11
申请号：US13540027
申请日：2012-07-02
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G01R33/50 , G01R33/561 , G01R33/563
CPC分类号： G01R33/50 , G01R33/5614 , G01R33/5616 , G01R33/56341
摘要： Magnetic resonance (MR) imaging methods and apparatus for simultaneous measurement of the physical properties R1 relaxation rate, R2 relaxation rate, proton density (PD), and apparent diffusion coefficient using a single magnetic resonance acquisition using a single gradient echo acquisition type. A method includes, from an MR scanner, obtaining at least three parallel, segmented gradient-echo acquisitions of a common acquisition type; in a computer, interleaving the at least three parallel, segmented gradient-echo acquisitions with a R1-sensitizing phase, a R2 sensitizing phase and a delay time; and in the computer, generating measures for R1 relaxation rate and R2 relaxation rate and PD from the at least three parallel, segmented gradient-echo acquisitions, thereby simultaneously estimating multiple physical parameters using the single gradient echo acquisition type.
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公开(公告)号：US09041393B2
公开(公告)日：2015-05-26
申请号：US12509022
申请日：2009-07-24
申请人： Marcel Warntjes
发明人： Marcel Warntjes
IPC分类号： G01R33/56 , G01R33/561
CPC分类号： G01R33/5602 , G01R33/50 , G01R33/5615 , G01R33/5616 , G01R33/5617
摘要： A magnetic resonance sequence includes an interleaved slice-selective pre-pulse and a slice-selective multi-echo acquisition. This sequence is repeated with different delays between the pre-pulse and the acquisition resulting in a matrix of complex images. Based on this matrix T1 and T2 relaxations, proton density and the B1 field can be estimated. These quantified parameters enable synthetic magnetic resonance imaging (MRI) and form a robust input for tissue segmentation in computer aided diagnosis for MRI.
摘要翻译： 磁共振序列包括交错切片选择性预脉冲和切片选择性多回波采集。 在预脉冲和采集之间以不同的延迟重复该序列，导致复杂图像的矩阵。 基于该矩阵T1和T2弛豫，可以估计质子密度和B1场。 这些量化的参数使得合成磁共振成像（MRI）并且在MRI的计算机辅助诊断中形成用于组织分割的鲁棒输入。
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公开(公告)号：US07443163B2
公开(公告)日：2008-10-28
申请号：US11575151
申请日：2005-08-19
IPC分类号： G01V3/00
CPC分类号： G01R33/3657 , G01R33/34007 , G01R33/3628
摘要： A low profile radio frequency coil (32, 44, 441, 442, 443) for use in a magnetic resonance imaging system includes a low profile antenna (34, 102, 202, 302) that is configured to resonate at about a magnetic resonance frequency of the magnetic resonance imaging system. A generally planar inductor (110, 112, 210, 240, 310) is electrically connected or coupled with the low profile antenna. The generally planar inductor provides selected frequency filtering of a radio frequency signal received by or transmitted by the low profile antenna.
摘要翻译： 一种用于磁共振成像系统的低频无线电频率线圈（32,44,44个，44个，44个3）包括 配置为在磁共振成像系统的大约磁共振频率下谐振的低剖面天线（34,102,202,302）。 大体上平面的电感器（110,112,210,240,310）与薄型天线电连接或耦合。 通常平面的电感器提供由低轮廓天线接收或由低轮廓天线发送的射频信号的选择的频率滤波。
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