公开(公告)号：US20220228222A1

公开(公告)日：2022-07-21

申请号：US17609517

申请日：2020-05-08

申请人： Christopher Goodnow ,  Megan Barnet ,  Katherine Jackson ,  Jonathan Cebon ,  Andreas Behren ,  Garvan Institute of Medical Research ,  Olivia Newton-John Cancer Research Institute

发明人： Christopher Goodnow ,  Megan Barnet ,  Katherine Jackson ,  Jonathan Cebon ,  Andreas Behren

IPC分类号： C12Q1/6886 ,  A61P35/04 ,  C07K16/28 ,  C07K16/18 ,  A61P35/00

摘要： The present disclosure relates to predicting a patient's response to cancer therapy based on the presence or absence of loss of function NOD-2 variants, as well as methods of treating cancer comprising inhibiting NOD-2 function.