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公开(公告)号:US06489331B1
公开(公告)日:2002-12-03
申请号:US09719570
申请日:2001-04-09
申请人: Junichi Shimada , Yoshihisa Ohta , Kotaro Takasaki , Miho Suda , Hideaki Kusaka , Hiroshi Yano , Satoshi Nakanishi , Yuzuru Matsuda
发明人: Junichi Shimada , Yoshihisa Ohta , Kotaro Takasaki , Miho Suda , Hideaki Kusaka , Hiroshi Yano , Satoshi Nakanishi , Yuzuru Matsuda
IPC分类号: A61K3152
CPC分类号: C07D487/14 , A61K31/505 , A61K31/519 , Y10S514/866
摘要: A medicament for the therapeutic treatment of diabetes which comprises as an active ingredient a compound represented by the general formula (I): wherein R1 represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, R2 represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aromatic heterocyclic group, R3 represents a hydrogen atom, a lower alkyl group or a substituted or unsubstituted aralkyl group, X1 and X2 independently represent a hydrogen atom, a lower alkyl group, a substituted or unsubstituted aralkyl group, or a substituted or unsubstituted aryl group, and the symbol “n” represents an integer of from 0 to 3, or a physiologically acceptable salt thereof.
摘要翻译: 一种用于治疗糖尿病的药物,其包含作为活性成分的由通式(I)表示的化合物:其中R 1表示氢原子,低级烷基,取代或未取代的芳基或取代或未取代的芳族 杂环基,R2表示氢原子,低级烷基,取代或未取代的芳烷基,取代或未取代的芳基或取代或未取代的芳香族杂环基,R3表示氢原子,低级烷基或取代 或未取代的芳烷基,X 1和X 2独立地表示氢原子,低级烷基,取代或未取代的芳烷基或取代或未取代的芳基,符号“n”表示0〜3的整数,或 其生理上可接受的盐。