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公开(公告)号：US08728410B2
公开(公告)日：2014-05-20
申请号：US13033351
申请日：2011-02-23
IPC分类号： B03C1/02
CPC分类号： B01D21/0009 , B01D2221/10 , B03C1/288 , B03C2201/18 , B03C2201/26 , C07K1/145 , C07K1/22 , C12N15/1006 , Y10T436/25375 , Y10T436/2575
摘要： A device and method are provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a phase-gate zone for receiving an isolation buffer therein. An output zone receives a reagent therein. A force is movable between a first position adjacent the input zone and a second position adjacent the output zone. The force urges the fraction-bound solid phase substrate from the input zone, through the phase-gate zone and into the output zone.
摘要翻译： 提供了一种用于促进从生物样品中提取级分的装置和方法。 生物样品包括非期望的材料和分数结合的固相底物。 该装置包括用于在其中接收生物样本的输入区和用于在其中接收隔离缓冲器的相门区。 输出区在其中接收试剂。 力可在邻近输入区的第一位置与邻近输出区的第二位置之间移动。 力从输入区域通过相位闸区促进分数结合的固相基板进入输出区域。
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公开(公告)号：US20140065654A1
公开(公告)日：2014-03-06
申请号：US13604192
申请日：2012-09-05
CPC分类号： G01N1/34 , B01L3/502761 , B01L3/502792 , B01L2200/0668 , B01L2200/0673 , B01L2300/087 , B01L2400/043 , G01N1/4077 , G01N35/0098
摘要： A device and a method are provided for isolating a fraction in a biological sample. The fraction is bound to solid phase substrate to define a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a second zone for receiving an isolation fluid therein. A force is provided that is generally perpendicular to gravity. The force is movable between a first position adjacent the input zone and a second position adjacent the isolation zone. The force captures the fraction-bound solid phase substrate and the fraction-bound solid phase substrate moves from the input zone to the isolation zone in response to the force moving from the first position to the second position.
摘要翻译： 提供了用于分离生物样品中的级分的装置和方法。 该馏分与固相底物结合以限定分馏结合的固相底物。 该装置包括用于在其中接收生物样品的输入区和用于在其中接收隔离流体的第二区。 提供通常垂直于重力的力。 该力可在邻近输入区的第一位置与邻近隔离区的第二位置之间移动。 该力捕获分馏结合的固相底物，并且部分结合的固相基板响应于从第一位置移动到第二位置的力而从输入区移动到隔离区。
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公开(公告)号：US20130158240A1
公开(公告)日：2013-06-20
申请号：US13326832
申请日：2011-12-15
申请人： David Beebe , Lindsay Strolman , Scott M. Berry
发明人： David Beebe , Lindsay Strolman , Scott M. Berry
摘要： A method is provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The method includes the steps of capturing the fraction-bound solid phase substrate and bringing an isolation buffer and the fraction-bound solid phase substrate into contact to purify the captured fraction-bound solid phase substrate.
摘要翻译： 提供了一种便于从生物样品中萃取级分的方法。 生物样品包括非期望的材料和分数结合的固相底物。 该方法包括以下步骤：捕获部分结合的固相底物并使分离缓冲液和分馏结合的固相底物接触以净化捕获的部分结合的固相底物。
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公开(公告)号：US08728411B2
公开(公告)日：2014-05-20
申请号：US13604192
申请日：2012-09-05
CPC分类号： G01N1/34 , B01L3/502761 , B01L3/502792 , B01L2200/0668 , B01L2200/0673 , B01L2300/087 , B01L2400/043 , G01N1/4077 , G01N35/0098
摘要： A device and a method are provided for isolating a fraction in a biological sample. The fraction is bound to solid phase substrate to define a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a second zone for receiving an isolation fluid therein. A force is provided that is generally perpendicular to gravity. The force is movable between a first position adjacent the input zone and a second position adjacent the isolation zone. The force captures the fraction-bound solid phase substrate and the fraction-bound solid phase substrate moves from the input zone to the isolation zone in response to the force moving from the first position to the second position.
摘要翻译： 提供了用于分离生物样品中的级分的装置和方法。 该馏分与固相底物结合以限定分馏结合的固相底物。 该装置包括用于在其中接收生物样品的输入区和用于在其中接收隔离流体的第二区。 提供通常垂直于重力的力。 该力可在邻近输入区的第一位置与邻近隔离区的第二位置之间移动。 该力捕获分馏结合的固相底物，并且部分结合的固相基板响应于从第一位置移动到第二位置的力而从输入区移动到隔离区。
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公开(公告)号：US20110212509A1
公开(公告)日：2011-09-01
申请号：US13033351
申请日：2011-02-23
CPC分类号： B01D21/0009 , B01D2221/10 , B03C1/288 , B03C2201/18 , B03C2201/26 , C07K1/145 , C07K1/22 , C12N15/1006 , Y10T436/25375 , Y10T436/2575
摘要： A device and method are provided for facilitating extraction of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a phase-gate zone for receiving an isolation buffer therein. An output zone receives a reagent therein. A force is movable between a first position adjacent the input zone and a second position adjacent the output zone. The force urges the fraction-bound solid phase substrate from the input zone, through the phase-gate zone and into the output zone.
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