公开(公告)号：US6086787A

公开(公告)日：2000-07-11

申请号：US233592

申请日：1999-01-19

申请人： Fred Schambil ,  Ulrich Zeidler ,  Soraya Shamsai ,  Thomas Foerster ,  Holger Tesmann

发明人： Fred Schambil ,  Ulrich Zeidler ,  Soraya Shamsai ,  Thomas Foerster ,  Holger Tesmann

IPC分类号： A61K8/30 ,  A61K8/02 ,  A61K8/06 ,  A61K8/31 ,  A61K8/34 ,  A61K8/37 ,  A61K8/39 ,  A61K8/73 ,  A61K8/92 ,  A61K9/107 ,  A61Q19/00 ,  B01F17/00 ,  B01J13/00

CPC分类号： A61K8/062 ,  A61K8/068 ,  A61K8/342 ,  A61K8/375 ,  A61K9/1075 ,  A61Q19/00 ,  B01F17/0092 ,  Y10S514/846 ,  Y10S514/938 ,  Y10S514/943

摘要： Process for the preparation of oil-in-water creams comprising the steps ofI forming a low-viscosity, very fine particle oil-in-water emulsion by heating the following composition to a temperature within or above its phase inversion temperature range:A) 1 part by weight of liquid oil component,B) from about 0.1 to about 0.5 parts by weight of at least one nonionic emulsifier having an HLB value of from 11 to 15,C) from about 0.1 to about 0.2 parts by weight of at least one co-emulsifier selected from saturated fatty alcohols containing 16 to 22 carbon atoms and partial esters of polyols containing 3 to 6 carbon atoms with saturated fatty acids containing 143 to 22 carbon atoms, andD) from about 1 to about 6 parts by weight of water; andII thickening the emulsion from step I to the consistency of a cream by adding thereto at least one consistency generator selected from co-emulsifiers defined in step I C) above and water-soluble polymers, wherein the thickened emulsion exhibits plastic behavior at 20.degree. C. with a yield point of at least about 5 Pascal.

摘要翻译： 水包油乳膏的制备方法，包括以下步骤：通过将下列组合物加热到其相转变温度范围内或之上的温度，形成低粘度，极细颗粒水包油乳液：A） 1重量份液体油组分，B）约0.1至约0.5重量份的至少一种HLB值为11至15的非离子乳化剂，C）至少约0.1至约0.2重量份 一种共乳化剂，其选自含有16-22个碳原子的饱和脂肪醇和含有3-6个碳原子的多元醇与含有143至22个碳原子的饱和脂肪酸的部分酯，以及D）约1至约6重量份的 水; 和II，通过向其中加入至少一种选自上述步骤IC中定义的共乳化剂的稠度产生剂和水溶性聚合物，将乳液从步骤I增稠至奶油的稠度，其中增稠的乳液在20℃表现出塑性 屈服点至少约为5帕斯卡。