公开(公告)号：US20210198332A1

公开(公告)日：2021-07-01

申请号：US17105858

申请日：2020-11-27

Applicant: ACADEMIA SINICA

Inventor： Benjamin Pang-Hsien TU ,  Rita PY CHEN ,  Joseph Jen-Tse HUANG ,  Yijuang CHERN ,  Yu-Song JANG ,  Xiang-Me LAI ,  Tai-Yan LIAO ,  Te-Hsien KUNG

IPC: C07K14/47

Abstract: Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.