公开(公告)号：US20200324117A1

公开(公告)日：2020-10-15

申请号：US16384528

申请日：2019-04-15

Applicant: ADVANCED NEUROMODULATION SYSTEMS, INC.

Inventor： Simeng ZHANG ,  Alexander Kent

IPC: A61N1/36 ,  A61N1/05 ,  G06N5/04

Abstract: The present disclosure provides systems and methods for generating stimulation patterns. A computing device includes a processor, and a memory device communicatively coupled to the processor. The memory device includes instructions that, when executed, cause the processor to provide a plurality of inputs to a multi-objective modified binary particle swarm optimization (MOMBPSO) algorithm, and apply the MOMBPSO to a computational circuit model using the plurality of inputs to generate a plurality of candidate stimulation patterns, wherein the MOMBPSO is applied to the computational circuit model to optimize both i) therapy efficacy and ii) power utilization.

公开(公告)号：US20220152393A1

公开(公告)日：2022-05-19

申请号：US17589787

申请日：2022-01-31

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Alexander Kent ,  Jeffery M. Kramer

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/24

Abstract: In one embodiment, the present disclosure is directed to a method for providing a neural stimulation therapy to treat chronic pain of a patient. The method comprises: recording, using a neural sensing system, neural activity of the patient at one or more sites within the nervous system of the patient related to the chronic pain of the patient, modifying a computational neural modeling system to model the sensed neural activity of the patient; computing a respective neural response of the patient for each of a plurality of different temporal stimulation patterns using the modified computational neural modeling system; selecting, based on the respective neural responses, one of the plurality of temporal stimulation patterns; and programming an implantable stimulation system to provide the selected one of the plurality of temporal stimulation patterns to the patient to treat the chronic pain of the patient.