公开(公告)号：US11702541B2

公开(公告)日：2023-07-18

申请号：US16457920

申请日：2019-06-28

Applicant: Agency for Science, Technology and Research

Inventor： Madhavan Nallani ,  Eva-Kathrin Ehmoser ,  Madanagopal Kunnavakkam

IPC: C08L71/02 ,  C08G65/329 ,  C08F220/52

CPC classification number: C08L71/02 ,  C08F220/52 ,  C08G65/329 ,  C08L2203/02

Abstract: Disclosed is a vesicular system comprising a surface with a vesicle immobilized thereon. The immobilized vesicle has a circumferential membrane of an amphiphilic polymer. The vesicle is coupled to a surface by means of a molecule with a non-polar moiety. The non-polar moiety comprises a main chain of 3 to about 30 carbon atoms and 0 to about 12 heteroatoms selected from Si, O, S, and Se. The molecule with the non-polar moiety is coupled to the surface via a covalent or non-covalent bond. A portion of the non-polar moiety is integrated in the circumferential membrane.

公开(公告)号：US09962438B2

公开(公告)日：2018-05-08

申请号：US14646008

申请日：2013-11-11

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Madhavan Nallani ,  Fabien Decaillot ,  Zhikang Fu ,  Xingfang Su

IPC: A61K39/385 ,  A61K47/34 ,  A61K9/127 ,  A61K9/00 ,  A61K39/12 ,  A61K39/00

CPC classification number: A61K39/385 ,  A61K9/0019 ,  A61K9/1273 ,  A61K39/12 ,  A61K47/34 ,  A61K2039/55566 ,  A61K2039/6093 ,  C12N2760/16134

Abstract: The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for the immunogen.

公开(公告)号：US20150297711A1

公开(公告)日：2015-10-22

申请号：US14646008

申请日：2013-11-11

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Madhavan Nallani ,  Fabien Decaillot ,  Zhikang Fu ,  Xingfang Su

IPC: A61K39/145 ,  C12N7/00 ,  A61K39/385 ,  A61K39/085 ,  A61K9/127

CPC classification number: A61K39/385 ,  A61K9/0019 ,  A61K9/1273 ,  A61K39/12 ,  A61K47/34 ,  A61K2039/55566 ,  A61K2039/6093 ,  C12N2760/16134

Abstract: The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for the immunogen.

Abstract translation: 本发明涉及引发针对免疫原的免疫应答的方法，特别涉及使用聚合物囊泡作为免疫原载体的方法。

公开(公告)号：US11241494B2

公开(公告)日：2022-02-08

申请号：US15939232

申请日：2018-03-28

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Madhavan Nallani ,  Fabien Decaillot ,  Zhikang Fu ,  Xingfang Su

IPC: A61K39/385 ,  A61K47/34 ,  A61K9/127 ,  A61K9/00 ,  A61K39/12 ,  A61K39/00

Abstract: The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for immunogen.

公开(公告)号：US20180214540A1

公开(公告)日：2018-08-02

申请号：US15939232

申请日：2018-03-28

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Madhavan Nallani ,  Fabien Decaillot ,  Zhikang Fu ,  Xingfang Su

IPC: A61K39/385 ,  A61K47/34 ,  A61K9/127 ,  A61K39/12 ,  A61K9/00 ,  A61K39/00

CPC classification number: A61K39/385 ,  A61K9/0019 ,  A61K9/1273 ,  A61K39/12 ,  A61K47/34 ,  A61K2039/55566 ,  A61K2039/6093 ,  C12N2760/16134

Abstract: The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for immunogen.