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    7-Azaindole fused heterocyclic compounds
    3.
    发明授权
    7-Azaindole fused heterocyclic compounds 失效
    7-Azaindole稠合杂环化合物

    公开(公告)号：US3880870A

    公开(公告)日：1975-04-29

    申请号：US46407774

    申请日：1974-04-25

    Applicant: AMERICAN HOME PROD

    Inventor： LEDIG KURT W ,  HERBST DAVID R

    IPC: C07D471/22 ,  C07D57/04

    CPC classification number: C07D471/22

    Abstract: WHERE R is hydrogen, alkyl of from 1 to 7 carbon atoms, or allyl; R1 is methyl, ethyl, or n-propyl; R2 is alkyl of from 1 to 7 carbon atoms or allyl; R3 is hydrogen or methyl and n is 1 or 2, or the pharmacologically acceptable acid addition salts thereof have analgesic activity.

    Compounds of the formulae:

    Abstract translation: 下列化合物：

    1ob-methyl-13b-polycarbonalkylgon-4-en-3-ones
    4.
    发明授权
    1ob-methyl-13b-polycarbonalkylgon-4-en-3-ones 失效
    1-10B-METHYL-13B-聚碳酸二氢喹啉-4-烯-3-酮

    公开(公告)号：US3607889A

    公开(公告)日：1971-09-21

    申请号：US3607889D

    申请日：1966-05-19

    Applicant: AMERICAN HOME PROD

    Inventor： STRIKE DONALD P ,  HERBST DAVID R ,  SMITH HERCHEL

    IPC: C07C169/20

    Abstract: 13-Aklyl-10-methylgon-4-en-3-ones possessing androgenic, anabolic, progestational activity are prepared from the correspondingly substituted 13-alkyl-10-methylgonan-4-ones wherein groups labile to mesylation are protected to permit selective mesylation of subsequently formed 4-hydroxy group, by converting the 4-one to its 3-hydroxy-methylene derivative, hydrolyzing the oximino group, mesylating the 4-hydroxy group, catalytically hydrogenating the unsaturation at the 4-position, and eliminating the 4-mexyloxy group to form the 4-en-3-one conjugated system.

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