公开(公告)号：US20230302264A1

公开(公告)日：2023-09-28

申请号：US18022245

申请日：2021-09-02

Applicant: AMGEN INC.

Inventor： Mehran Mojarrad ,  Scott R. Gibson ,  Scott Castanon ,  Robert Eisele ,  Dylann Ceriani

IPC: A61M31/00 ,  A61M37/00

CPC classification number: A61M31/002 ,  A61M37/0015

Abstract: A swallowable drug delivery device includes a capsule and a tissue attachment member. The capsule may contain a drug and may be sized to pass through at least a portion of the gastrointestinal tract of a patient. The tissue attachment member may be coupled to the capsule. In an initial state, the tissue attachment member may allow the capsule to pass through the at least a portion of the gastrointestinal tract of the patient. In an activated state, the tissue attachment member is configured to at least selectively attach the capsule to a wall of the gastrointestinal tract of the patient. The tissue attachment member may be configured to change from the initial state to the activated state in response to an in vivo condition associated with a predetermined location in the gastrointestinal tract of the patient.