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公开(公告)号:US20160145333A1
公开(公告)日:2016-05-26
申请号:US14899551
申请日:2014-06-25
Applicant: AMGEN INC.
Inventor: Peter COWARD , Steven A. MOORE, Jr. , Shi-Yuan MENG , Mei-Mei TSAI , Chadwick Terence KING , Aaron Avraham NAZARIAN
IPC: C07K16/28
CPC classification number: C07K16/28 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: This disclosure relates to CB1 receptor antigen-binding proteins, e.g. antibodies and methods of using the CB1 receptor antibodies. The CB1 receptor antibodies may comprise an antagonistic antibody to CB1 receptors and may be used to treat various health conditions. The health conditions can comprise obesity or diabetes or any disease that benefits from antagonism of the CB1 receptor.
Abstract translation: 本公开涉及CB1受体抗原结合蛋白,例如 抗体和使用CB1受体抗体的方法。 CB1受体抗体可以包含对CB1受体的拮抗性抗体,并且可以用于治疗各种健康状况。 健康状况可以包括肥胖症或糖尿病或从CB1受体的拮抗作用中受益的任何疾病。