公开(公告)号：US20140277343A1

公开(公告)日：2014-09-18

申请号：US13840402

申请日：2013-03-15

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Weiying Zhao

IPC: A61L31/16 ,  A61F2/958

CPC classification number: A61L31/16 ,  A61F2/915 ,  A61F2250/0067 ,  A61L31/10 ,  A61L2300/42 ,  A61L2300/45

Abstract: A drug delivery device for reducing the likelihood of stent thrombosis following implantation in a subject is provided. A stent is provided including a body having a plurality of struts and one or more coatings applied to the body including at least one polymer, a therapeutic agent for inhibiting restenosis, a loading dose of a first antiplatelet agent and a maintenance dose of the first antiplatelet agent, and a loading dose of a second antiplatelet agent and a maintenance dose of the second antiplatelet agent.

Abstract translation: 本发明提供一种用于降低植入患者后支架血栓形成的可能性的药物输送装置。 提供一种支架，其包括具有多个支柱的主体和施加于身体的一个或多个涂层，包括至少一种聚合物，用于抑制再狭窄的治疗剂，第一抗血小板剂的负荷剂量和第一抗血小板的维持剂量 药剂和第二抗血小板剂的负荷剂量和第二抗血小板剂的维持剂量。

公开(公告)号：US10748659B2

公开(公告)日：2020-08-18

申请号：US14643154

申请日：2015-03-10

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Weiying Zhao ,  Dong Li

IPC: G16H50/30

Abstract: Assessing a risk associated with implantation of a drug delivery device configured to treat blood vessels, is described. Particularly, devices, methods, and systems for assessing the risk of stent thrombosis, prior to implantation, for determining the appropriate stent and/or medication regimen for a particular patient, and continuing to assess the risk of stent thrombosis after implantation, thereby improving the efficacy of the therapy, are described. Other embodiments are described and claimed.

公开(公告)号：US20160267243A1

公开(公告)日：2016-09-15

申请号：US14643154

申请日：2015-03-10

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Weiying Zhao ,  Dong Li

IPC: G06F19/00

Abstract: The disclosed subject matter relates to assessing the risk associated with implantation of a drug delivery device configured to treat blood vessels. Particularly, the present disclosed subject matter is directed to devices, methods, and systems for assessing the risk of stent thrombosis, prior to implantation, for determining the appropriate stent and/or medication regimen for a particular patient, and continuing to assess the risk of stent thrombosis after implantation, thereby improving the efficacy of the therapy.

Abstract translation: 所公开的主题涉及评估与植入用于治疗血管的药物递送装置相关联的风险。 特别地，本公开的主题涉及用于在植入之前评估支架血栓形成的风险用于确定特定患者的适当的支架和/或药物治疗方案的装置，方法和系统，并且继续评估 植入术后支架内血栓形成，从而提高治疗效果。

公开(公告)号：US10010655B2

公开(公告)日：2018-07-03

申请号：US13840402

申请日：2013-03-15

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Weiying Zhao

IPC: A61F2/06 ,  A61L31/16 ,  A61L31/10 ,  A61F2/915

CPC classification number: A61L31/16 ,  A61F2/915 ,  A61F2250/0067 ,  A61L31/10 ,  A61L2300/42 ,  A61L2300/45

Abstract: A drug delivery device for reducing the likelihood of stent thrombosis following implantation in a subject is provided. A stent is provided including a body having a plurality of struts and one or more coatings applied to the body including at least one polymer, a therapeutic agent for inhibiting restenosis, a loading dose of a first antiplatelet agent and a maintenance dose of the first antiplatelet agent, and a loading dose of a second antiplatelet agent and a maintenance dose of the second antiplatelet agent.