公开(公告)号：US20200016064A1

公开(公告)日：2020-01-16

申请号：US16469118

申请日：2017-12-20

Applicant: Agency for Science, Technology and Research

Inventor： Yin Win Khin ,  Choon Peng Teng ,  Michelle Dela Cruz Regulacio ,  Si Yin Tee ,  Leng Duei Koh ,  Michelle Low ,  Xian Jun Loh ,  Ming Yong Han

IPC: A61K8/98 ,  A61Q1/02

Abstract: In the present invention, a method of producing a colourant-incorporated silk fibroin is provided. In a preferred embodiment, the method comprises the steps of: i) decrystallizing a degummed silk fibroin in the presence of an acidic solution or a metal salt solution (i.e. lithium bromide); ii) mixing one or more colourants with the decrystallized silk fibroin and iii) recrystallizing the decrystallized silk fibroin containing the colourants such that it forms a recrystallized region encapsulating the colourants, thereby obtaining the colourant-incorporated silk fibroin. In addition, a cosmetic product comprising the colourant-incorporated silk fibroin is provided.