公开(公告)号：US20160338968A1

公开(公告)日：2016-11-24

申请号：US15224818

申请日：2016-08-01

申请人： Alpharma Pharmaceuticals LLC

发明人： Frank Matthews ,  Alfred C. Liang ,  Frank Johnson

IPC分类号： A61K9/50 ,  A61K31/485

CPC分类号： A61K9/5047 ,  A61K9/00 ,  A61K9/2081 ,  A61K9/2086 ,  A61K9/209 ,  A61K9/5026 ,  A61K9/5073 ,  A61K9/5078 ,  A61K9/5084 ,  A61K31/485 ,  A61K45/06 ,  A61K2300/00

摘要： Provided herein is a method of treating a condition in a host that is responsive to an agonist, the method comprising administering to the host a multi-layer pharmaceutical composition comprising the agonist and an antagonist thereof, wherein the agonist and antagonist are not in direct contact with one another in the intact form of the composition.