专利检索 ap:("Andrea Castellin" OR "Luca Gregori" OR "Guadalupe Gonzales Trueba" OR "Albino Rubello" OR "Andrea Nicole") AND inv:"Albino Rubello" 第 1 页

1.

发明申请
Process for the synthesis and purification of (4-methoxybutyl) (4-trifluoromethylphenyl) methanone 审中-公开
标题翻译：（4-甲氧基丁基）（4-三氟甲基苯基）甲酮的合成和纯化方法

公开(公告)号：US20090264680A1

公开(公告)日：2009-10-22

申请号：US11630866

申请日：2004-07-07

申请人： Andrea Castellin , Luca Gregori , Guadalupe Gonzales Trueba , Albino Rubello , Andrea Nicole

发明人： Andrea Castellin , Luca Gregori , Guadalupe Gonzales Trueba , Albino Rubello , Andrea Nicole

IPC分类号： C07C45/00

CPC分类号： C07C45/81 , C07C45/004 , C07C45/82 , C07C49/84

摘要： A process for the preparation of 4-trifluoromethylvalerophenone is described. The process described is a three step process comprising the synthesis of organomagnesium specie, coupling reaction between the organomagnesium specie and trifluoromethylbenzonitrile or trifluoromethylbenzoyl chloride and preferably a purification of the product obtained in suitable reaction conditions. In the process an extraction phase of the final product is not required.

摘要翻译： 描述了制备4-三氟甲基戊酰氯的方法。所述方法是包括合成有机镁物质，有机镁物质和三氟甲基苄腈或三氟甲基苯甲酰氯之间的偶联反应的三步法，优选在合适的反应条件下获得的产物的纯化。在此过程中，不需要最终产品的萃取阶段。