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公开(公告)号:US20180297985A1
公开(公告)日:2018-10-18
申请号:US15818082
申请日:2017-11-20
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D403/04 , A61K31/4184 , A61K9/00 , C07D405/14 , C07D401/14 , A61K45/06 , A61K31/506
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:USRE49556E1
公开(公告)日:2023-06-20
申请号:US17376199
申请日:2021-07-15
Applicant: Array BioPharma Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/506 , A61K9/00 , A61K31/4184 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14
CPC classification number: A61K31/506 , A61K9/0053 , A61K31/4184 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , A61K31/506 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US20180297986A1
公开(公告)日:2018-10-18
申请号:US15818264
申请日:2017-11-20
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D403/04 , A61K31/4184 , A61K9/00 , C07D405/14 , C07D401/14 , A61K45/06 , A61K31/506
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US09850229B2
公开(公告)日:2017-12-26
申请号:US15179385
申请日:2016-06-10
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D401/00 , C07D403/04 , C07D401/14 , A61K31/506 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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5.
公开(公告)号:US09593100B2
公开(公告)日:2017-03-14
申请号:US14994827
申请日:2016-01-13
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/535 , C07D403/04 , C07D401/14 , A61K31/506 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
Abstract translation: 本发明提供了一类新颖的化合物,包含这些化合物的药物组合物和使用这些化合物治疗或预防与异常或失调的激酶活性相关的疾病或病症的方法,特别是涉及B-Raf异常激活的疾病或病症。
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公开(公告)号:US20230116233A1
公开(公告)日:2023-04-13
申请号:US17724589
申请日:2022-04-20
Applicant: Array BioPharma Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/506 , C07D401/14 , C07D403/04 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US20200323852A1
公开(公告)日:2020-10-15
申请号:US16741937
申请日:2020-01-14
Applicant: Array BioPharma Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/506 , C07D401/14 , C07D403/04 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US10576080B2
公开(公告)日:2020-03-03
申请号:US15818082
申请日:2017-11-20
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/506 , A61K31/4184 , A61K9/00 , C07D405/14 , A61K45/06 , C07D403/04 , C07D401/14
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US10005761B2
公开(公告)日:2018-06-26
申请号:US15070905
申请日:2016-03-15
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: A61K31/535 , C07D403/04 , C07D401/14 , A61K31/506 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
CPC classification number: A61K31/506 , A61K9/0053 , A61K31/4184 , A61K45/06 , C07D401/14 , C07D403/04 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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公开(公告)号:US09850230B2
公开(公告)日:2017-12-26
申请号:US15179644
申请日:2016-06-10
Applicant: Array BioPharma, Inc.
Inventor: Shenlin Huang , Xianming Jin , Zuosheng Liu , Daniel Poon , John Tellew , Yongqin Wan , Xing Wang , Yongping Xie
IPC: C07D401/00 , C07D403/04 , C07D401/14 , A61K31/506 , A61K45/06 , C07D405/14 , A61K9/00 , A61K31/4184
CPC classification number: C07D403/04 , A61K9/0053 , A61K31/4184 , A61K31/506 , A61K45/06 , C07D401/14 , C07D405/14 , A61K2300/00
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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