公开(公告)号：US20170216266A1

公开(公告)日：2017-08-03

申请号：US15501908

申请日：2015-08-03

Applicant: BASF SE

Inventor： MARTIN VIERTELHAUS ,  Tiziana CHIODO ,  Beate SALVADOR ,  Marcus VOSSEN ,  Andreas HAFNER ,  Tobias HINTERMANN ,  Walter WEISHAAR ,  Rolf HELLMANN

IPC: A61K31/4402 ,  C07D213/40

CPC classification number: A61K31/4402 ,  C07D213/40

Abstract: The present invention primarily relates to multi-component crystals comprising a compound of formula 1 and a second compound selected from the group consisting of co-crystal formers and solvents. The invention is further related to pharmaceutical compositions comprising such multi-component crystals. Furthermore, the invention relates to processes for preparing said multi-component crystals. The invention also relates to several aspects of using said multi-component crystals or pharmaceutical compositions to treat a disease.