公开(公告)号：US09556179B2

公开(公告)日：2017-01-31

申请号：US14653895

申请日：2013-12-20

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Upender Velaparthi ,  Chetan Padmakar Darne ,  Dharmpal S. Dodd ,  Anthony J. Sampognaro ,  Mark D. Wittman ,  Selvakumar Kumaravel ,  Dibakar Mullick ,  Peiying Liu ,  Chandrasekhar Reddy Rachamreddy

IPC: C07D487/04 ,  C07D519/00

CPC classification number: C07D487/04 ,  C07D519/00

Abstract: The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.

Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐。 式（I）的化合物抑制蛋白激酶活性，从而使它们用作抗癌剂。

公开(公告)号：US20150344481A1

公开(公告)日：2015-12-03

申请号：US14653895

申请日：2013-12-20

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Upender Velaparthi ,  Chetan Padmakar Darne ,  Dharmpal S. Dodd ,  Anthony J. Sampognaro ,  Mark D. Wittman ,  Selvakumar Kumaravel ,  Dibakar Mullick ,  Peiying Liu ,  Chandrasekhar Reddy Rachamreddy

IPC: C07D487/04 ,  C07D519/00

CPC classification number: C07D487/04 ,  C07D519/00

Abstract: The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The compounds of Formula (I) inhibit protein kinase activity thereby making them useful as anticancer agents.

Abstract translation: 本发明提供式（I）化合物及其药学上可接受的盐。 式（I）的化合物抑制蛋白激酶活性，从而使它们用作抗癌剂。