专利检索 ap:("BROWN UNIVERSITY") AND inv:"Kyle A. Totaro" 第 1 页

1.

发明申请
Novel Syringolin Analogues and Methods of Making and Using Same 审中-公开

公开(公告)号：US20190010133A1

公开(公告)日：2019-01-10

申请号：US15570874

申请日：2016-05-07

申请人： Brown University

发明人： Jason K. Sello , Kyle A. Totaro

IPC分类号： C07D245/02 , A61P35/00

CPC分类号： C07D245/02 , A61K45/06 , A61P35/00 , C07D403/06

摘要： The present invention provides, in certain aspects, novel syringolin analogues, In certain embodiments, the compounds of the invention are proteasome inhibitors, In other embodiments, the compounds treat or prevent a cancer such as, but not limited to, leukemia in a subject.

2.

发明授权
Syringolin analogues and methods of making and using same 有权

公开(公告)号：US10597368B2

公开(公告)日：2020-03-24

申请号：US15570874

申请日：2016-05-07

申请人： BROWN UNIVERSITY

发明人： Jason K. Sello , Kyle A. Totaro

IPC分类号： A61K31/404 , A61P35/00 , C07D403/06 , C07D245/02

摘要： The present invention provides, in certain aspects, novel syringolin analogues, In certain embodiments, the compounds of the invention are proteasome inhibitors, In other embodiments, the compounds treat or prevent a cancer such as, but not limited to, leukemia in a subject.