公开(公告)号：US20210370296A1

公开(公告)日：2021-12-02

申请号：US17330663

申请日：2021-05-26

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan HANDIQUE ,  Ronald LEBOFSKY ,  Josh SHINOFF

IPC: B01L3/00 ,  B01L7/00 ,  C12Q1/6806

Abstract: Methods and systems for sample target molecules are provided.

公开(公告)号：US20250041846A1

公开(公告)日：2025-02-06

申请号：US18808643

申请日：2024-08-19

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Kalyan HANDIQUE ,  Ronald LEBOFSKY

IPC: B01L3/00 ,  B01L7/00 ,  C12Q1/686

Abstract: The invention(s) cover systems and methods for target detection in a multiplexed and rapid manner. Embodiments of the system can include: a base substrate; and an array of sample processing regions defined at a broad surface of the base substrate, wherein each of the array of sample processing regions includes: a set of microwell subarrays arranged in a gradient by volumetric capacity between an upstream end and a downstream end of each respective sample processing region, and a boundary separating each respective sample processing region from adjacent sample processing regions. The system can support methods, with example implementation by an automated platform, for returning preliminary results from a subset of microwells of the samples processing regions, as well as results pertaining to specific and non-specific amplification, for multiple targets of a sample.