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公开(公告)号:US20150291607A1
公开(公告)日:2015-10-15
申请号:US14683682
申请日:2015-04-10
发明人: Johanna BAKONYI , Steven Richard BRUNETTE , Delphine COLLIN , Robert Owen HUGHES , Xiang LI , Shuang LIANG , Robert SIBLEY , Michael Robert TURNER , Lifen WU , Qiang ZHANG
IPC分类号: C07D487/04
CPC分类号: C07D475/00 , A61K31/33 , C07D475/10 , C07D487/04
摘要: The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
摘要翻译: 本发明包括式(I)的化合物,其中本文所定义的变量适用于RORγ的调节和治疗与RORγ调节有关的疾病。 本发明还包括制备式(I)化合物和含有它们的药物制剂的方法。
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公开(公告)号:US20190002465A1
公开(公告)日:2019-01-03
申请号:US16123139
申请日:2018-09-06
发明人: Johanna BAKONYI , Steven Richard BRUNETTE , Delphine COLLIN , Robert Owen HUGHES , Xiang LI , Shuang LIANG , Robert SIBLEY , Michael Robert TURNER , Lifen WU , Qiang ZHANG
IPC分类号: C07D475/00 , C07D487/04 , C07D475/10 , A61K31/33
摘要: The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
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公开(公告)号:US20180022749A1
公开(公告)日:2018-01-25
申请号:US15426208
申请日:2017-02-07
发明人: Johanna BAKONYI , Steven Richard BRUNETTE , Delphine COLLIN , Robert Owen HUGHES , Xiang LI , Shuang LIANG , Robert SIBLEY , Michael Robert TURNER , Lifen WU , Qiang ZHANG
IPC分类号: C07D475/00 , C07D487/04 , C07D475/10 , A61K31/33
CPC分类号: C07D475/00 , A61K31/33 , C07D475/10 , C07D487/04
摘要: The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
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公开(公告)号:US20170008894A1
公开(公告)日:2017-01-12
申请号:US15270029
申请日:2016-09-20
发明人: Johanna BAKONYI , Steven Richard BRUNETTE , Delphine COLLIN , Robert Owen HUGHES , Xiang LI , Shuang LIANG , Robert SIBLEY , Michael Robert TURNER , Lifen WU , Qiang ZHANG
IPC分类号: C07D475/00
CPC分类号: C07D475/00 , A61K31/33 , C07D475/10 , C07D487/04
摘要: The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
摘要翻译: 其中本文所定义的变量适用于RORγ的调节和与RORγ调节有关的疾病的治疗。 本发明还包括制备式(I)化合物和含有它们的药物制剂的方法。
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公开(公告)号:US20210171527A1
公开(公告)日:2021-06-10
申请号:US16071147
申请日:2017-01-18
IPC分类号: C07D487/04 , A61P37/06
摘要: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
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公开(公告)号:US20160075706A1
公开(公告)日:2016-03-17
申请号:US14946873
申请日:2015-11-20
发明人: Johanna BAKONYI , Steven Richard BRUNETTE , Delphine COLLIN , Robert Owen HUGHES , Xiang LI , Shuang LIANG , Robert SIBLEY , Michael Robert TURNER , Lifen WU , Qiang ZHANG
IPC分类号: C07D475/00
CPC分类号: C07D475/00 , A61K31/33 , C07D475/10 , C07D487/04
摘要: The present invention encompasses compounds of the formula (I) wherein the variables are defined herein which are suitable for the modulation of RORγ and the treatment of diseases related to the modulation of RORγ. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
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