公开(公告)号：US06291726B1

公开(公告)日：2001-09-18

申请号：US09622285

申请日：2000-10-18

申请人： Bon-Su Lee ,  Kyoo-Hyun Chung ,  Yoon-Sik Lee ,  Young-Gyu Kim

发明人： Bon-Su Lee ,  Kyoo-Hyun Chung ,  Yoon-Sik Lee ,  Young-Gyu Kim

IPC分类号： C07C20500

CPC分类号： C07C201/08 ,  C07C205/06

摘要： The nitration of aromatic compounds is achieved in high yield and selectivity by using oxygen activated by an inorganic catalyst and nitrogen dioxide. Since this process uses neither concentration nitric nor sulfuric acids, the generation of spent waste acid does not occur. Furthermore, the process does not encounter the problem of high costs associated with the generation of ozone as in an alternative nitration process. Since the solubility of oxygen in a reaction medium is increased by using pressurized oxygen, nitrogen dioxide is activated by a porous inorganic oxide and thus an aromatic compound(e.g., benzene) is nitrated into a nitro compound (e.g., PhNO2), the reaction rate is significantly increased, and the recovery of reactants is easy due to the insolubility of the catalyst.

摘要翻译： 芳族化合物的硝化通过使用由无机催化剂和二氧化氮活化的氧而以高产率和选择性实现。 由于该方法既不使用浓硝酸还是硫酸，不会发生废废酸的产生。 此外，该过程不会像在替代硝化过程中那样遇到与臭氧产生相关的高成本的问题。 由于通过使用加压氧来增加氧在反应介质中的溶解度，因此二氧化氮被多孔无机氧化物活化，因此将芳族化合物（例如苯）硝化成硝基化合物（例如PhNO 2），反应速率 显着增加，并且由于催化剂的不溶性，反应物的回收容易。

公开(公告)号：US20080188655A1

公开(公告)日：2008-08-07

申请号：US12059515

申请日：2008-03-31

申请人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： C07D471/02 ,  C07D295/00

CPC分类号： C07D215/56 ,  A01N43/60 ,  A01N43/90 ,  C08F246/00

摘要： The present invention relates to a monomer with anti-microbial characteristics, a polymeric compound with anti-microbial characteristics using the same, and manufacturing methods thereof, and more particularly, to an antimicrobial monomer comprising a saturated or unsaturated hydrocarbon having a polymerizable functional group within its structure. Also, the present invention provides a polymeric compound using the above antimicrobial monomer, a manufacturing method thereof, and a polymeric resin composition.The compounds according to the present invention have durable antimicrobial activity and high heat resistance, they do not give rise to toxicity when added to conventional resins by not eluting the antimicrobial compounds, and they do not have an effect on the properties of molded products.

摘要翻译： 本发明涉及具有抗微生物特性的单体，具有抗微生物特性的聚合物及其制造方法，更具体地说涉及包含具有聚合官能团的饱和或不饱和烃的抗微生物单体， 其结构。 此外，本发明提供使用上述抗微生物单体的聚合物，其制造方法和聚合物树脂组合物。 根据本发明的化合物具有耐久的抗菌活性和高耐热性，当通过不洗脱抗微生物化合物而添加到常规树脂中时它们不会引起毒性，并且它们对成型产品的性质没有影响。

公开(公告)号：US07777033B2

公开(公告)日：2010-08-17

申请号：US12059515

申请日：2008-03-31

申请人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： C07D215/38 ,  C07D403/04 ,  C07D487/04

CPC分类号： C07D215/56 ,  A01N43/60 ,  A01N43/90 ,  C08F246/00

摘要： The present invention relates to a monomer with anti-microbial characteristics, a polymeric compound with anti-microbial characteristics using the same, and manufacturing methods thereof, and more particularly, to an antimicrobial monomer comprising a saturated or unsaturated hydrocarbon having a polymerizable functional group within its structure according to formula (1) in which the respective moieties have the meanings defined in the following specification. Also, the present invention provides a polymeric compound using the above antimicrobial monomer, a manufacturing method thereof, and a polymeric resin composition. The compounds according to the present invention have durable antimicrobial activity and high heat resistance, they do not give rise to toxicity when added to conventional resins by not eluting the antimicrobial compounds, and they do not have an effect on the properties of molded products.

摘要翻译： 本发明涉及具有抗微生物特性的单体，具有抗微生物特性的聚合物及其制造方法，更具体地说涉及包含具有聚合官能团的饱和或不饱和烃的抗微生物单体， 其结构式（1）其中各部分具有以下说明书中定义的含义。 此外，本发明提供使用上述抗微生物单体的聚合物，其制造方法和聚合物树脂组合物。 根据本发明的化合物具有耐久的抗菌活性和高耐热性，当通过不洗脱抗微生物化合物而添加到常规树脂中时它们不会引起毒性，并且它们对成型产品的性质没有影响。

公开(公告)号：US07491768B2

公开(公告)日：2009-02-17

申请号：US10519345

申请日：2003-06-25

申请人： Woong-Sig Moon ,  Jae-Chul Kim ,  Youn-Seop Byoun ,  Kyoo-Hyun Chung ,  Heun-Soo Kang ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woong-Sig Moon ,  Jae-Chul Kim ,  Youn-Seop Byoun ,  Kyoo-Hyun Chung ,  Heun-Soo Kang ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： C08L1/00

CPC分类号： C08K5/0058

摘要： The present invention relates to an anti-microbial or anti-coagulating polymer resin and a method for preparing the same, and a medical appliance or instrument using the same, and more particularly to a method for preparing an anti-microbial or anti-coagulating medical polymer resin comprising the steps of simply mixing a polymer resin with at least one kind of pharmaceutically active material without using a solvent. The pharmaceutically active material is preferably an anti-microbial or anti-coagulant. According to the present invention, an anti-microbial or anti-coagulating material that is safe to a human body is mixed with a polymer resin by simple addition in an environmentally favorable non-solvent method, thereby maintaining superior anti-microbial effects even after high temperature molding, minimizing a released amount of anti-microbial to increase anti-microbial effect durability, and solving a toxic problem in a body. Therefore, the present invention can be extensively applied for medical appliances/instruments for a human body.

摘要翻译： 本发明涉及一种抗微生物或抗凝聚合物树脂及其制备方法，以及使用该抗微生物或抗凝血性聚合物树脂的医疗器具或器具，更具体地涉及一种制备抗微生物或抗凝血性医疗 聚合物树脂包括在不使用溶剂的情况下简单地将聚合物树脂与至少一种药学活性材料混合的步骤。 药物活性物质优选为抗菌剂或抗凝剂。 根据本发明，通过在环境友好的非溶剂方法中简单添加，将对人体安全的抗微生物或抗凝剂材料与聚合物树脂混合，从而即使在高温下也保持优异的抗微生物效果 温度成型，最大限度地减少抗微生物的释放量，增加抗菌效果的耐久性，并解决身体中的毒性问题。 因此，本发明可以广泛地应用于人体的医疗用具/器具。

公开(公告)号：US07361719B2

公开(公告)日：2008-04-22

申请号：US10503040

申请日：2003-02-03

申请人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： C08F20/26 ,  C08F26/06

CPC分类号： C07D215/56 ,  A01N43/60 ,  A01N43/90 ,  C08F246/00

摘要： The present invention relates to a monomer with anti-microbial characteristics, a polymeric compound with anti-microbial characteristics using the same, and manufacturing methods thereof, and more particularly, to an antimicrobial monomer comprising a saturated hydrocarbon having a polymerizable functional group within its structure. Also, the present invention provides a polymeric compound using the above antimicrobial monomer, a manufacturing method thereof, and a polymeric resin composition. The compounds according to the present invention have durable antimicrobial activity and high heat resistance, they do not give rise to toxicity when added to conventional resins by not eluting the antimicrobial compounds, and they do not have an effect on the properties of molded products.

摘要翻译： 本发明涉及具有抗微生物特性的单体，具有抗微生物特性的聚合化合物及其制造方法，更具体地说，涉及包含在其结构内具有聚合性官能团的饱和烃的抗微生物单体 。 此外，本发明提供使用上述抗微生物单体的聚合物，其制造方法和聚合物树脂组合物。 根据本发明的化合物具有耐久的抗菌活性和高耐热性，当通过不洗脱抗微生物化合物而添加到常规树脂中时它们不会引起毒性，并且它们对成型产品的性质没有影响。

公开(公告)号：US20050245671A1

公开(公告)日：2005-11-03

申请号：US10519345

申请日：2003-06-25

申请人： Woeng-Sig Moon ,  Jae-Chul Kim ,  Youn-Seop Byoun ,  Kyoo-Hyun Chung ,  Heun-Soo Kang ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woeng-Sig Moon ,  Jae-Chul Kim ,  Youn-Seop Byoun ,  Kyoo-Hyun Chung ,  Heun-Soo Kang ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： A61M1/16 ,  A61F2/06 ,  A61F2/28 ,  A61F2/30 ,  A61F2/54 ,  A61F2/60 ,  A61L27/00 ,  A61L31/00 ,  A61L33/00 ,  A61M25/00 ,  C08K5/00 ,  C08K5/3445 ,  C08L1/00

CPC分类号： C08K5/0058

摘要： The present invention relates to an anti-microbial or anti-coagulating polymer resin and a method for preparing the same, and a medical appliance or instrument using the same, and more particularly to a method for preparing an anti-microbial or anti-coagulating medical polymer resin comprising the steps of simply mixing a polymer resin with at least one kind of pharmaceutically active material without using a solvent. The pharmaceutically active material is preferably an anti-microbial or anti-coagulant. According to the present invention, an anti-microbial or anti-coagulating material that is safe to a human body is mixed with a polymer resin by simple addition in an environmentally favorable non-solvent method, thereby maintaining superior anti-microbial effects even after high temperature molding, minimizing a released amount of anti-microbial to increase anti-microbial effect durability, and solving a toxic problem in a body. Therefore, the present invention can be extensively applied for medical appliances/instruments for a human body.

摘要翻译： 本发明涉及一种抗微生物或抗凝聚合物树脂及其制备方法，以及使用该抗微生物或抗凝血性聚合物树脂的医疗器具或器具，更具体地涉及一种制备抗微生物或抗凝血性医疗 聚合物树脂包括在不使用溶剂的情况下简单地将聚合物树脂与至少一种药学活性材料混合的步骤。 药物活性物质优选为抗菌剂或抗凝剂。 根据本发明，通过在环境友好的非溶剂方法中简单添加，将对人体安全的抗微生物或抗凝剂材料与聚合物树脂混合，从而即使在高温下也保持优异的抗微生物效果 温度成型，最大限度地减少抗微生物的释放量，增加抗菌效果的耐久性，并解决身体中的毒性问题。 因此，本发明可以广泛地应用于人体的医疗用具/器具。

公开(公告)号：US20050176905A1

公开(公告)日：2005-08-11

申请号：US10503040

申请日：2003-02-03

申请人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

发明人： Woong-Sig Moon ,  Jae-Chul Kim ,  Kyoo-Hyun Chung ,  Ki-Oh Kong ,  Jung-Hwa Hwang

IPC分类号： C07D403/10 ,  A01N43/60 ,  A01N43/90 ,  C07D215/56 ,  C08F246/00 ,  C08F26/06

CPC分类号： C07D215/56 ,  A01N43/60 ,  A01N43/90 ,  C08F246/00

摘要： The present invention relates to a monomer with anti-microbial characteristics, a polymeric compound with anti-microbial characteristics using the same, and manufacturing methods thereof, and more particularly, to an antimicrobial monomer comprising a saturated hydrocarbon having a polymerizable functional group within its structure. Also, the present invention provides a polymeric compound using the above antimicrobial monomer, a manufacturing method thereof, and a polymeric resin composition. The compounds according to the present invention have durable antimicrobial activity and high heat resistance, they do not give rise to toxicity when added to conventional resins by not eluting the antimicrobial compounds, and they do not have an effect on the properties of molded products.

摘要翻译： 本发明涉及具有抗微生物特性的单体，具有抗微生物特性的聚合化合物及其制造方法，更具体地说，涉及包含在其结构内具有聚合性官能团的饱和烃的抗微生物单体 。 此外，本发明提供使用上述抗微生物单体的聚合物，其制造方法和聚合物树脂组合物。 根据本发明的化合物具有耐久的抗菌活性和高耐热性，当通过不洗脱抗微生物化合物而添加到常规树脂中时它们不会引起毒性，并且它们对成型产品的性质没有影响。