Voltage Controlled Pulse Sequences for Irreversible Electroporation Ablations

    公开(公告)号:US20220233237A1

    公开(公告)日:2022-07-28

    申请号:US17582733

    申请日:2022-01-24

    Abstract: At least some embodiments of the present disclosure are directed to an electroporation ablation system for treating targeted tissue in a patient. The electroporation ablation system comprises an ablation catheter including catheter electrodes configured to generate electric fields in the targeted tissue in response to a plurality of electrical pulse sequences delivered in a plurality of therapy sections; a controller configured to receive a first pulse voltage of a first electrical pulse sequence measured during a first therapy section of the plurality of therapy sections; and determine a charge voltage based on the first pulse voltage; and an electroporation generator. The electroporation generator is operatively coupled to the catheter electrodes and the controller and configured to deliver a second electrical pulse sequence at a controlled pulse voltage for a second therapy section of the plurality of therapy sections.

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