公开(公告)号：US20220388998A1

公开(公告)日：2022-12-08

申请号：US17621567

申请日：2020-06-26

Applicant: CHDI Foundation, Inc

Inventor： Michel C. Maillard ,  Matthew R. Lee ,  Celia Dominguez ,  Michael Barnes ,  Alan F. Haughan ,  Tammy Ladduwahetty ,  Christopher A. Luckhurst ,  Andrew J. Stott ,  Jason Tierney

IPC: C07D413/14 ,  C07D401/04 ,  C07D405/14 ,  C07D471/04 ,  C07D213/75 ,  C07D487/04 ,  C07D487/08

Abstract: Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.