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公开(公告)号：US20090298505A1
公开(公告)日：2009-12-03
申请号：US12084484
申请日：2006-10-10
摘要： A mobile radio communications network is disclosed in which zones may be defined for provision of location based services and applications. Various methods are also disclosed for using the defined zones in different ways for different applications. The methods include associating users with zones, updating users of zones with changes to the zones, controlling zone size and dynamically uploading zone profiles to users based on the user's geographical location.
摘要翻译： 公开了一种移动无线电通信网络，其中可以定义哪些区域用于提供基于位置的服务和应用。 还公开了针对不同应用以不同方式使用限定区域的各种方法。 这些方法包括将用户与区域相关联，更新区域的用户，对区域进行更改，控制区域大小以及根据用户的地理位置向用户动态上传区域配置文件。
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公开(公告)号：US20090075651A1
公开(公告)日：2009-03-19
申请号：US11887948
申请日：2006-04-10
IPC分类号： H04W4/00
CPC分类号： H04W64/00 , G01S5/0036 , G01S5/0252 , G01S5/14
摘要： Methods and systems for determining whether a mobile radio terminal is on or out of a zone in a radio communications network. The methods and systems provide for generating a profile representative of the zone using measurements taken by the mobile radio terminal and/or the network and/or using predicted values. A comparison is then made between subsequent measurements or values and the profile to make a determination as to whether the mobile radio terminal is in or out of the zone. The methods and systems are applicable to any zone-based application including differential call charging, security applications, buddy finder services, mobile gaming and location based services in general.
摘要翻译： 用于确定移动无线电终端是否在无线电通信网络中的区域之外的方法和系统。 所述方法和系统提供使用由移动无线电终端和/或网络进行的测量和/或使用预测值来生成代表该区域的简档。 然后在随后的测量或值和简档之间进行比较，以确定移动无线电终端是否在区域内或外。 方法和系统适用于任何基于区域的应用，包括差分呼叫计费，安全应用，好友查找器服务，移动游戏和基于位置的服务。
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公开(公告)号：US20090011779A1
公开(公告)日：2009-01-08
申请号：US11887949
申请日：2006-04-10
CPC分类号： H04W64/00 , G01S5/0036 , G01S5/0252 , G01S5/14
摘要： A method and system for calculating the location of a mobile radio terminal in a radio communications network. The method provides for the collection of measurements of radio signal parameters at the mobile radio terminal which are then processed and transmitted to a network processor for calculating the location of the mobile radio terminal. The collected measurements may be filtered and subsets of the measurements may also be selected according to their suitability for particular applications.
摘要翻译： 一种用于计算无线电通信网络中的移动无线电终端的位置的方法和系统。 该方法提供了在移动无线电终端处收集无线电信号参数的测量值，然后将其处理并发送到网络处理器以计算移动无线电终端的位置。 可以过滤收集的测量值，也可以根据其对特定应用的适用性来选择测量的子集。
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4.发明授权Systems and methods for mobile terminal location determination using radio signal parameter measurements 有权使用无线电信号参数测量的移动终端位置确定的系统和方法公开(公告)号：US08700069B2
公开(公告)日：2014-04-15
申请号：US11887949
申请日：2006-04-10
IPC分类号： H04W24/00
CPC分类号： H04W64/00 , G01S5/0036 , G01S5/0252 , G01S5/14
摘要： A method and system for calculating the location of a mobile radio terminal in a radio communications network. The method provides for the collection of measurements of radio signal parameters at the mobile radio terminal which are then processed and transmitted to a network processor for calculating the location of the mobile radio terminal. The collected measurements may be filtered and subsets of the measurements may also be selected according to their suitability for particular applications.
摘要翻译： 一种用于计算无线电通信网络中的移动无线电终端的位置的方法和系统。 该方法提供了在移动无线电终端处收集无线电信号参数的测量值，然后将其处理并发送到网络处理器以计算移动无线电终端的位置。 可以过滤收集的测量值，也可以根据其对特定应用的适用性来选择测量的子集。
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5.发明授权Systems and methods for mobile terminal location determination using profiles of radio signal parameter measurements 有权使用无线电信号参数测量概况进行移动终端位置确定的系统和方法公开(公告)号：US08463285B2
公开(公告)日：2013-06-11
申请号：US11887948
申请日：2006-04-10
IPC分类号： H04W24/00
CPC分类号： H04W64/00 , G01S5/0036 , G01S5/0252 , G01S5/14
摘要： Methods and systems for determining whether a mobile radio terminal is on or out of a zone in a radio communications network. The methods and systems provide for generating a profile representative of the zone using measurements taken by the mobile radio terminal and/or the network and/or using predicted values. A comparison is then made between subsequent measurements or values and the profile to make a determination as to whether the mobile radio terminal is in or out of the zone. The methods and systems are applicable to any zone-based application including differential call charging, security applications, buddy finder services, mobile gaming and location based services in general.
摘要翻译： 用于确定移动无线电终端是否在无线电通信网络中的区域之外的方法和系统。 所述方法和系统提供使用由移动无线电终端和/或网络进行的测量和/或使用预测值来生成代表该区域的简档。 然后在随后的测量或值和简档之间进行比较，以确定移动无线电终端是否在区域内或外。 方法和系统适用于任何基于区域的应用，包括差分呼叫计费，安全应用，好友查找器服务，移动游戏和基于位置的服务。
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公开(公告)号：US08870883B2
公开(公告)日：2014-10-28
申请号：US13016774
申请日：2011-01-28
CPC分类号： A61B17/155 , A61B17/02 , A61B17/14 , A61B17/142 , A61B17/157
摘要： Various method and apparatuses may be used to perform a procedure, such as a resection of a portion of the anatomy for preparation of the implants of a prosthetic. Various resecting member, including saw blades having selected geometries and shapes, can be used to assist in the resection of an anatomy to provide for implantation of a prosthetic. In addition, a cutting block assembly may be used to guide the resecting member. The cutting block assembly may be moveably mounted relative to the portion to be resected.
摘要翻译： 可以使用各种方法和装置来执行手术，例如切除解剖结构的一部分以准备假体的植入物。 可以使用包括具有选定几何形状和形状的锯片的各种切除构件来辅助切除解剖结构以提供假体植入。 此外，可以使用切割块组件来引导切除部件。 切割块组件可相对于要切除的部分可移动地安装。
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公开(公告)号：US08663956B2
公开(公告)日：2014-03-04
申请号：US13588322
申请日：2012-08-17
IPC分类号： C12N1/15
CPC分类号： C12N15/8243 , C12N9/88
摘要： Provided herein are host cells comprising carbonic anhydrase activity, wherein the cells are capable of producing C4-dicarboxylic acid. Also provided are methods of producing C4-dicarboxylic acid comprising (a) cultivating the host cells having carbonic anhydrase activity in a medium under suitable conditions to produce C4-dicarboxylic acid; and (b) recovering the C4-dicarboxylic acid.
摘要翻译： 本文提供了包含碳酸酐酶活性的宿主细胞，其中细胞能够产生C4-二羧酸。 还提供了生产C4-二羧酸的方法，其包括（a）在合适条件下培养在培养基中具有碳酸酐酶活性的宿主细胞以产生C4-二羧酸; 和（b）回收C4-二羧酸。
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公开(公告)号：US08597180B2
公开(公告)日：2013-12-03
申请号：US13166878
申请日：2011-06-23
申请人： Thomas John Hector Copeland , Cormac O'Prey , Rebecca Ann Wilkins , Daniel Leonard Fuller , Stephen Brown , Christopher John Silk , Trevor Beckett
发明人： Thomas John Hector Copeland , Cormac O'Prey , Rebecca Ann Wilkins , Daniel Leonard Fuller , Stephen Brown , Christopher John Silk , Trevor Beckett
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B17/3423 , A61B17/3431 , A61B17/3439 , A61B2017/0225 , A61B2017/3427 , A61B2017/3488
摘要： A surgical access assembly for positioning within an opening in tissue including an outer member positionable outside a patient and defining an opening therein to receive a surgical instrument. The outer member has a first portion and a second portion wherein at least one of the first and second portions is movable with respect to the other portion. The assembly also includes an inner member positionable within a patient and a flexible member extending between the inner member and outer member, wherein movement of one of the first and second portions of the outer member adjusts tension on the flexible member to retract tissue. A locking mechanism locks the outer member in a plurality of select expanded positions. The locking mechanism includes first engagement structure on the first portion engageable with the second portion and a slidable member movable to a locking position to retain the first and second portions in the select expanded position.
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公开(公告)号：US08574886B2
公开(公告)日：2013-11-05
申请号：US13401663
申请日：2012-02-21
申请人： Regine Behr , William Widner , Maria Tang , Stephen Brown , Leslie Naggiar , Linda Sternberg
发明人： Alan Sloma , Regine Behr , William Widner , Maria Tang , David Sternberg , Stephen Brown
IPC分类号： C12N1/20 , C12N15/74 , C12N15/00 , C12P19/04 , C12P19/26 , C12P19/28 , C12P1/00 , C12P21/06 , C07H21/04
CPC分类号： C12P19/26 , C12N9/1051 , C12N15/52
摘要： The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein the Bacillus host cell comprises a nucleic acid construct comprising a hyaluronan synthase encoding sequence operably linked to a promoter sequence foreign to the hyaluronan synthase encoding sequence; and (b) recovering the hyaluronic acid from the cultivation medium. The present invention also relates to an isolated nucleic acid sequence encoding a hyaluronan synthase operon comprising a hyaluronan synthase gene and a UDP-glucose 6-dehydrogenase gene, and optionally one or more genes selected from the group consisting of a UDP-glucose pyrophosphorylase gene, UDP-N-acetylglucosamine pyrophosphorylase gene, and glucose-6-phosphate isomerase gene. The present invention also relates to isolated nucleic acid sequences encoding a UDP-glucose 6-dehydrogenase, UDP-glucose pyrophosphorylase, and UDP-N-acetylglucosamine pyrophosphorylase.
摘要翻译： 本发明涉及透明质酸的制备方法，其包括：（a）在适于产生透明质酸的条件下培养芽孢杆菌属宿主细胞，其中所述芽孢杆菌宿主细胞包含可操作地连接的透明质酸合酶编码序列的核酸构建体 涉及透明质酸合酶编码序列外源的启动子序列; 和（b）从培养基中回收透明质酸。 本发明还涉及编码包含透明质酸合酶基因和UDP-葡萄糖-6-脱氢酶基因的透明质酸合酶操纵子的分离的核酸序列，以及任选地一种或多种选自UDP-葡萄糖焦磷酸化酶基因， UDP-N-乙酰葡糖胺焦磷酸化酶基因和葡萄糖-6-磷酸异构酶基因。 本发明还涉及编码UDP-葡萄糖-6-脱氢酶，UDP-葡萄糖焦磷酸化酶和UDP-N-乙酰葡糖胺焦磷酸化酶的分离的核酸序列。
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公开(公告)号：US20120041269A1
公开(公告)日：2012-02-16
申请号：US13166878
申请日：2011-06-23
申请人： Thomas John Hector Copeland , Cormac O'Prey , Rebecca Ann Wilkins , Daniel Leonard Fuller , Stephen Brown , Christopher John Silk , Trevor Beckett
发明人： Thomas John Hector Copeland , Cormac O'Prey , Rebecca Ann Wilkins , Daniel Leonard Fuller , Stephen Brown , Christopher John Silk , Trevor Beckett
IPC分类号： A61B1/32
CPC分类号： A61B17/0218 , A61B17/3423 , A61B17/3431 , A61B17/3439 , A61B2017/0225 , A61B2017/3427 , A61B2017/3488
摘要： A surgical access assembly for positioning within an opening in tissue including an outer member positionable outside a patient and defining an opening therein to receive a surgical instrument. The outer member has a first portion and a second portion wherein at least one of the first and second portions is movable with respect to the other portion. The assembly also includes an inner member positionable within a patient and a flexible member extending between the inner member and outer member, wherein movement of one of the first and second portions of the outer member adjusts tension on the flexible member to retract tissue. A locking mechanism locks the outer member in a plurality of select expanded positions. The locking mechanism includes first engagement structure on the first portion engageable with the second portion and a slidable member movable to a locking position to retain the first and second portions in the select expanded position.
摘要翻译： 一种用于定位在组织中的开口内的外科进入组件，包括可定位在患者外部并在其中限定其中的开口以接收外科器械的外部构件。 外部构件具有第一部分和第二部分，其中第一和第二部分中的至少一个可相对于另一部分移动。 组件还包括可定位在患者体内的内部构件和在内部构件和外部构件之间延伸的柔性构件，其中外部构件的第一和第二部分中的一个的运动调节柔性构件上的张力以缩回组织。 锁定机构将外部构件锁定在多个选择的扩张位置。 锁定机构包括可与第二部分接合的第一部分上的第一接合结构和可移动到锁定位置以将第一和第二部分保持在选择扩张位置的可滑动构件。
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