公开(公告)号：US20230343570A1

公开(公告)日：2023-10-26

申请号：US18016162

申请日：2021-07-12

Applicant: DH Technologies Development Pte. Ltd.

Inventor： Takashi BABA ,  Kaoru KARASAWA

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/0045 ,  H01J49/062

Abstract: In one aspect, a method of performing mass spectrometry is disclosed, which comprises ionizing a plurality of oligonucleotides to generate a plurality of negatively charged oligonucleotide ions, and interacting a plurality of charged reagent ions with the negatively charged oligonucleotide ions to reduce the negative charge state of the negatively charged oligonucleotide ions.