-
公开(公告)号:US20090098103A1
公开(公告)日:2009-04-16
申请号:US12082662
申请日:2008-04-11
CPC分类号: C07K14/745 , A61K38/00 , A61K38/36 , A61K45/06 , A61K2300/00
摘要: Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.
摘要翻译: 提供了修饰的因子VII多肽及其用途。 这种修饰的FVII多肽包括因子VIIa和其他形式的因子VII。 所提供的经修饰的FVII多肽是那些具有改变的活性,通常改变的促凝活性,包括增加的促凝活性。 因此,这些修饰的多肽是治疗剂。
-
公开(公告)号:US20100166729A9
公开(公告)日:2010-07-01
申请号:US12082662
申请日:2008-04-11
CPC分类号: C07K14/745 , A61K38/00 , A61K38/36 , A61K45/06 , A61K2300/00
摘要: Modified factor VII polypeptides and uses thereof are provided. Such modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities. Hence, such modified polypeptides are therapeutics.
摘要翻译: 提供了修饰的因子VII多肽及其用途。 这种修饰的FVII多肽包括因子VIIa和其他形式的因子VII。 所提供的经修饰的FVII多肽是那些具有改变的活性,通常改变的促凝活性,包括增加的促凝活性。 因此,这些修饰的多肽是治疗剂。
-