公开(公告)号：US20230330234A1

公开(公告)日：2023-10-19

申请号：US17796671

申请日：2021-02-01

Applicant: FREIE UNIVERSITÄT BERLIN

Inventor： Rainer HAAG ,  Magda FERRARO ,  Ehsan MOHAMMADIFAR ,  Michael SCHIRNER

IPC: A61K47/34 ,  A61K9/107 ,  A61K31/404 ,  A61K31/506 ,  A61K31/519 ,  A61K31/4545 ,  A61K9/19 ,  B01J13/08

CPC classification number: A61K47/34 ,  A61K9/1075 ,  A61K31/404 ,  A61K31/506 ,  A61K31/519 ,  A61K31/4545 ,  A61K9/19 ,  B01J13/08

Abstract: It is provided a composition comprising a hyperbranched polyester polyol derivative and a small molecule comprising at least one cyclic amine. The hyperbranched polyester polyol derivative is obtainable by a method comprising the following steps: a) reacting only glycidol and ε-caprolactone at a temperature lying in a range of between 40° C. and 140° C. to obtain a hyperbranched polyester polyol derivative in which caprolactone residues and glycerol residues are randomly arranged; b) reacting the hyperbranched polyester polyol derivative of step a) with a sulfation reagent to obtain a sulfated hyperbranched polyester polyol as hyperbranched polyester polyol derivative.