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1.发明申请NEW FLUORENE DERIVATIVES, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF AS INHIBITORS OF THE PROTEIN CHAPERONE HSP 90 有权新的荧光衍生物，其组合物和作为蛋白质CHAPERONE HSP 90的抑制剂的用途公开(公告)号：US20100130503A1
公开(公告)日：2010-05-27
申请号：US12625005
申请日：2009-11-24
申请人： Fabienne THOMPSON , Patrick MAILLIET , Jean-Marie RUXER , Helene GOULAOUIC , François VALLEE , Herve MINOUX , Fabienne PILORGE , Luc BERTIN , Stephane HOURCADE , Maria MENDEZ-PEREZ , Peter HAMLEY
发明人： Fabienne THOMPSON , Patrick MAILLIET , Jean-Marie RUXER , Helene GOULAOUIC , François VALLEE , Herve MINOUX , Fabienne PILORGE , Luc BERTIN , Stephane HOURCADE , Maria MENDEZ-PEREZ , Peter HAMLEY
IPC分类号： A61K31/437 , C07D471/04 , A61K31/47 , A61K31/498 , A61K31/519 , A61K31/44 , A61P25/00 , A61P25/18 , A61P31/12 , A61P35/00
CPC分类号： C07D403/12 , C07D401/12 , C07D471/04 , C07D487/04
摘要： The present invention relates to compounds of formula (I): wherein R1, R2, R2′, L, Het, p and p′ are as defined herein, compositions containing them, and their use as medicinal products.
摘要翻译： 本发明涉及式（I）化合物：其中R1，R2，R2'，L，Het，p和p'如本文所定义，含有它们的组合物及其作为药用产品的用途。
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2.发明申请2-CARBAMIDE-4-PHENYLTHIAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF 失效2-碳酰胺-4-苯并噻唑衍生物，其制备方法及其治疗方法公开(公告)号：US20090018117A1
公开(公告)日：2009-01-15
申请号：US12146898
申请日：2008-06-26
IPC分类号： A61K31/551 , C07D417/12 , C07D417/14 , A61K31/496
CPC分类号： C07D277/46 , C07D417/12 , C07D417/14
摘要： The disclosure relates to 2-carbamide-4-phenylthiazole derivatives having the following general formula (I): wherein R1, R2, R3, Y and p are as defined in the disclosure. The disclosure also relates to pharmaceutical compositions containing a compound of formula (I), to processes for preparing the compounds of formula (I), and to methods of using the compounds of formula (I).
摘要翻译： 本公开涉及具有以下通式（I）的2-氨基-4-苯基噻唑衍生物：其中R1，R2，R3，Y和p如本公开所定义。 本公开还涉及含有式（I）化合物的药物组合物，其用于制备式（I）化合物的方法，以及使用式（I）化合物的方法。
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