摘要:
3-pyrrolo[b]cyclohexylene-2-dihydro-indolinone derivatives of formula (I) or their pharmaceutically acceptable salts and uses thereof. The intermediates of formula (II) for preparing the above compounds. The bioassay shows that the above compounds and their pharmaceutically acceptable salts can modulate the activity of protein kinases (PKs), inhibit the activity of tyrosine kinases (PTKs) and inhibit many kinds of tumor cells as well as.
摘要:
3-pyrrolo[b]cyclohexylene-2-dihydro-indolinone derivatives of formula (I) or their pharmaceutically acceptable salts and uses thereof. The intermediates of formula (II) for preparing the above compounds. The bioassay shows that the above compounds and their pharmaceutically acceptable salts can modulate the activity of protein kinases (PKs), inhibit the activity of tyrosine kinases (PTKs) and inhibit many kinds of tumor cells as well as.
摘要:
Method and system for operating a fitness exercise equipment are provided. In a preferred embodiment of the present disclosure, a system for operating a fitness exercise equipment comprises a processor and a memory device electronically coupled to the processor, the memory device storing instructions which, when executed by the processor, direct the processor to acquire an initial exercise parameters entered by a user, determine an initial exercise program based on the initial exercise parameters, and initiate movement of the fitness exercise equipment in correspondence with the initial exercise program, where the instruction to acquire the initial exercise parameters comprises instructions to detect commands entered by the user via built-in touch screen of the fitness exercise equipment, wherein instructions to detect commands entered by the user via built-in touch screen comprises detecting a curve drawn by the user on the built-in touch screen.
摘要:
The invention provides variants of the Clostridium thermocellum endoglucanase (CelG) that have improved endoglucanase activity compared to the wild type enzyme. Also provided are related polynucleotides, compositions, vectors, host cells, and methods of use.
摘要:
An electrical connection includes a first wire bonded to adjacent bond pads proximate to an edge of a die and a second wire having one end bonded to a die bond pad distal to the die edge and a second end bonded to a lead finger of a lead frame or a connection pad of a substrate. The second wire crosses and is supported by the first wire. The first wire acts as a brace that prevents the second wire from touching the edge of the die. The first wire also prevents the second wire from excessive lateral movement during encapsulation.
摘要:
The invention relates to recombinant expression of a variant form of a fungal C1 strain β-glucosidase. The invention also relates to the generation of fermentable sugars from biomass and the production of biofuels by fermentation of the sugars using genetically modified organisms expressing the β-glucosidase variant. The invention provides methods for producing a fermentable sugar, such as glucose, from cellobiose by contacting cellobiose with a recombinant β-glucosidase variant protein, such as a variant protein secreted by a recombinant host cell into culture medium. Methods of the invention may be used for conversion of a biomass substrate to a fermentable sugar, and ultimately to ethanol or other biofuel.
摘要:
The present invention relates to valve current control method based on modular multi-level converter, this method includes the control of the low frequency oscillations of the current and that of double frequency harmonic component; For said low frequency oscillations of the current, the control method includes some steps as below: first, calculate the half of the sum of the upper arm current and the lower arm current, it is the valve DC current component, said DC current component is arm circulating current; Secondly, comparing the actual value of the arm circulating current to setting value of that, the error is obtained, after some signal processing, additional output set voltage is obtained. For said the double frequency harmonic component of current, the control method includes some steps as below: firstly, figure out capacitor voltage fluctuation prediction value of the sub module; secondly, the output voltage is divided by the sum of the sub module reference voltage and the capacitor voltage fluctuation prediction value, and get the actual output set number of sub module. This method not only can realize stability of the dynamic performance of the system, but also can suppress the arm double frequency harmonic component, at the same time under the abnormal conditions of the AC system; the valve current has good output characteristics.
摘要:
A mechanism is described for facilitating power extension service at computing devices according to one embodiment of the invention. A method of embodiments of the invention includes calculating potential power saving by one or more of a plurality of power-saving techniques supported by a computing device. The calculating includes identifying the one or more of the plurality of power-saving techniques that are available for selection and an expected amount of power to be saved with the one or more of the plurality of power saving techniques. The method may further include generating a list identifying the one or more of the plurality of power-saving techniques and relevant information resulting from the calculation, anddisplaying the list.
摘要:
Substituted saccharide compounds, dental compositions comprising substituted saccharide compounds, and methods of using dental compositions are described. In one embodiment, the substituted saccharide amide compound comprises a hydrophobic group and at least one free-radically polymerizable group with the proviso that the hydrophobic group is not bonded to the ethylenically unsaturated carbon atom of the free-radically polymerizable group. The hydrophobic group is typically bonded to a nitrogen atom of a saccharide amine residue or a carbonyl moiety of saccharide amide residue.
摘要:
A method, apparatus, and computer program product for realizing application high availability are provided. The application is installed on both a first node and a second node, the first node being used as an active node, and the second node being used as a passive node. The method includes: monitoring access operations to files by an application during its execution on the active node; replicating the monitored updates to the file by the application from the active node to a storage device accessible to the passive node if the application performs updates to a file during the access operations; sniffing the execution of the application on the active node; and switching the active node to the second node and initiating the application on the second node in response to sniffing a failure in the execution of the application on the active node.