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1.发明公开公开(公告)号：US20240034812A1
公开(公告)日：2024-02-01
申请号：US18025203
申请日：2021-09-10
Applicant: GENMAB A/S
Inventor： Brian ELLIOTT , Tahamtan AHMADI , Christopher W.L. CHIU , Esther C.W. BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/565 , C07K2317/31
Abstract: Provided are methods of clinical treatment of diffuse large B-cell lymphoma (DLBCL) (e.g., previously untreated, high-risk DLBCL) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimen of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
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2.发明公开公开(公告)号：US20240301078A1
公开(公告)日：2024-09-12
申请号：US18500799
申请日：2023-11-02
Applicant: GENMAB A/S
Inventor： Brian ELLIOTT , Tahamtan AHMADI , Christopher W.L. CHIU , Esther C.W. BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
IPC: C07K16/28 , A61K31/475 , A61K31/573 , A61K31/675 , A61K31/704 , A61K39/00 , A61K39/395 , A61P35/00 , C07K16/46
CPC classification number: C07K16/2887 , A61K31/475 , A61K31/573 , A61K31/675 , A61K31/704 , A61K39/3955 , A61P35/00 , C07K16/2809 , C07K16/468 , A61K2039/505 , A61K2039/507 , A61K2039/545 , C07K2317/24 , C07K2317/31 , C07K2317/565
Abstract: Provided are methods of clinical treatment of diffuse large B-cell lymphoma (DLBCL) (e.g., previously untreated, high-risk DLBCL) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimen of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
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公开(公告)号：US20230312757A1
公开(公告)日：2023-10-05
申请号：US18025202
申请日：2021-09-10
Applicant: GENMAB A/S
Inventor： Brian ELLIOTT , Jenny J. CHEN , Tahamtan AHMADI , Christopher W.L. CHIU , Esther C.W. BRElJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/565 , C07K2317/31
Abstract: Provided are methods of clinical treatment of chromic lymphoblastic leukemia (CLL) inhuman subjects using a bispecific-antibody which binds to CD3 and CD20.
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公开(公告)号：US20220119544A1
公开(公告)日：2022-04-21
申请号：US17558430
申请日：2021-12-21
Applicant: GENMAB A/S
Inventor： Brian Elliott , Tahamtan AHMADI , Christopher W.L. CHIU , Esther C.W BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
IPC: C07K16/28 , A61P35/00 , A61K31/675 , A61K39/395 , A61K31/704 , A61K31/475 , A61K31/573
Abstract: Provided are methods of clinical treatment of diffuse large B-cell lymphoma (DLBCL) (e.g., previously untreated, high-risk DLBCL) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimen of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone).
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Patent Agency Ranking
5.发明公开公开(公告)号：US20230312758A1
公开(公告)日：2023-10-05
申请号：US18025204
申请日：2021-09-10
Applicant: GENMAB A/S
Inventor： Brian ELLIOTT , Tahamtan AHMADI , cHRISTOPHER W.L. CHIU , Esther C.W. BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
CPC classification number: C07K16/468 , A61P35/00 , C07K2317/565 , C07K2317/31
Abstract: Provided are methods of clinical treatment of follicular lymphoma (for example, relapsed and/or refractory follicular lymphoma) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimens of rituximab and lenalidomide.
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公开(公告)号：US20230227570A1
公开(公告)日：2023-07-20
申请号：US17923317
申请日：2021-05-07
Applicant: GENMAB A/S
Inventor： Tahamtan AHMADI , Manish GUPTA , Tommy R. LI , Roberto OLIVERI , Dena DEMARCO , Ida HIEMSTRA , Christopher CHIU , Brian ELLIOTT , Ada AZARYAN
CPC classification number: C07K16/2887 , C07K16/2809 , A61P35/00 , C07K2317/31 , A61K39/00
Abstract: The present invention relates to bispecific antibodies (bsAbs) and the use of such antibodies in the treatment of disease in subjects. Moreover, advantageous treatment regimens are provided for the treatment of B-cell Non-Hodgkin Lymphoma (B-NHL).
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7.发明申请公开(公告)号：US20220144964A1
公开(公告)日：2022-05-12
申请号：US17559938
申请日：2021-12-22
Applicant: GENMAB A/S
Inventor： Brian ELLIOTT , Tahamtan AHMADI , Christopher W. L. CHIU , Esther C. W. BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
IPC: C07K16/28 , A61K31/454
Abstract: Provided are methods of clinical treatment of follicular lymphoma (for example, relapsed and/or refractory follicular lymphoma) in human subjects using a bispecific antibody which binds to CD3 and CD20 in combination with standard of care regimens of rituximab and lenalidomide.
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公开(公告)号：US20220112287A1
公开(公告)日：2022-04-14
申请号：US17559935
申请日：2021-12-22
Applicant: GENMAB A/S
Inventor： Brian Elliott , Jenny Jianlin CHEN , Tahamtan AHMADI , Christopher W.L. CHIU , Esther C.W. BREIJ , Ida HIEMSTRA , Maria N. JURE-KUNKEL
IPC: C07K16/28
Abstract: Provided are methods of clinical treatment of chronic lymphoblastic leukemia (CLL) in human subjects using a bispecific antibody which binds to CD3 and CD20.
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公开(公告)号：US20210371538A1
公开(公告)日：2021-12-02
申请号：US17314946
申请日：2021-05-07
Applicant: GENMAB A/S
Inventor： Tahamtan AHMADI , Manish GUPTA , Tommy LI , Roberto OLIVERI , Dena DEMARCO , Ida HIEMSTRA , Christopher CHIU , Brian ELLIOTT , Ada AZARYAN
IPC: C07K16/28 , A61K31/573 , A61K45/06 , A61K39/395 , A61P35/00
Abstract: The present invention relates to bispecific antibodies (bsAbs) and the use of such antibodies in the treatment of disease in subjects. Moreover, advantageous treatment regimens are provided for the treatment of B-cell Non-Hodgkin Lymphoma (B-NHL).
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