公开(公告)号：US20230312757A1

公开(公告)日：2023-10-05

申请号：US18025202

申请日：2021-09-10

Applicant: GENMAB A/S

Inventor： Brian ELLIOTT ,  Jenny J. CHEN ,  Tahamtan AHMADI ,  Christopher W.L. CHIU ,  Esther C.W. BRElJ ,  Ida HIEMSTRA ,  Maria N. JURE-KUNKEL

IPC: C07K16/46 ,  A61P35/00

CPC classification number: C07K16/468 ,  A61P35/00 ,  C07K2317/565 ,  C07K2317/31

Abstract: Provided are methods of clinical treatment of chromic lymphoblastic leukemia (CLL) inhuman subjects using a bispecific-antibody which binds to CD3 and CD20.