公开(公告)号：US11814437B2

公开(公告)日：2023-11-14

申请号：US17938523

申请日：2022-10-06

Applicant: GENMAB A/S

Inventor： David Satijn ,  Patrick Engelberts ,  Kristel Kemper ,  Esther C. W. Breij ,  Simone Oostindie ,  Farshid Alemdehy

IPC: C07K16/28 ,  A61P35/00 ,  C12N15/63

CPC classification number: C07K16/2878 ,  A61P35/00 ,  C07K16/2809 ,  C12N15/63 ,  C07K2317/31 ,  C07K2317/526 ,  C07K2317/565

Abstract: The invention relates to multispecific antibodies binding to CD3 and CD30. The invention further provides pharmaceutical compositions comprising antibodies of the invention, nucleic acids encoding the antibodies, host cells that produce the antibodies, methods of producing the antibodies and uses of the antibodies, in particular for cancer therapy.